product summary
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company name :
NKMAX
product type :
antibody
product name :
Human Frataxin antibody
catalog :
ATGA0440
quantity :
50 ul
price :
170 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
AT10E11
reactivity :
human
application :
western blot, ELISA, immunocytochemistry
more info or order :
NKMAX product webpage
product information
Product Type :
Antibodies
Item Name :
Human Frataxin antibody
Catalog number (SKU) :
ATGA0440
NCBI :
NP_000135
Description :
Frataxin, also known as FXN, is an iron binding protein which belongs to FRATAXIN family. It is an anti-apoptotic protein which prevents mitochondrial damage, reactive oxygen species production and act as either an iron chaperone or an iron storage protein. Frataxin is localized to the mitochondrion and regulating mitochondrial iron transport and respiration. Defects in this protein cause Friedreich ataxia.
Alternative Names :
CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein.
Concentration :
1mg/ml (determined by BCA assay)
Formulation :
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Campuzano V., et al. (1996) Science. 271(5254): 1423-7. ;; Shan Y., et al. (2007) Hum Mol Genet. 16(8): 929-41.
Abs Host :
Mouse
Isotype :
IgG1 kappa
Immunogen :
Recombinant human Frataxin (42-210aa) purified from E. coli
Applications :
ELISA, WB, ICC/IF
IF Comment And Pic :
ICC/IF analysis of Frataxin in A549 cell line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human Frataxin antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
WB Comment and Pic :
The cell lysates (10ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Frataxin antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1. : 293T cell lysate ;;Lane 2. : Frataxin transfected 293T cell lysate
Reacts With :
Human
Clone Number :
AT10E11
Ab Usage :
The antibody has been tested by ELISA, Western blot analysis, and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species :
Human
Gene Category :
Signal Transduction
Conjugation :
Unconjugated
Clonality Mono VS Poly :
Monoclonal
Ab Purification Comment :
By protein-A affinity chromatography
Product Type Name :
Monoclonal Antibody
UniProt No. :
Q16595
Internal Search Terms :
Frataxin, CyaY, FA, FARR, FRDA, X25, FXN, Friedreich ataxia protein.,ATGA0440-10ug,ATGA0440-20ug,ATGA0440-50ug,ATGA0440-100ug,ATGA0440-250ug,ATGA0440-500ug,ATGA0440-1mg,ATGA0440-10,ATGA0440-20,ATGA0440-50,ATGA0440-100,ATGA0440-250,ATGA0440-500,ATGA0440-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.