Human CDC37 antibody | NKMAX ATGA0428 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human CDC37 antibody

catalog :

ATGA0428

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT3G7

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human CDC37 antibody

Catalog number (SKU) :

ATGA0428

NCBI :

NP_008996

Description :

The protein encoded by this gene is highly similar to CDC37, a cell division cycle control protein of Saccharomyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF1, MOK, as well as eIF-2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Alternative Names :

Cell division cycle 37 homolog, P50CDC37, CDC37, Cell division cycle 37 homolog, Cell division cycle 37 homolog S cerevisiae hypothetical protein CDC37, CDC 37, CDC37 cell division cycle 37 homolog, Cdc37 homolog, CDC37 protein, Hsp90 chaperone protein kinase targeting subunit, Hsp90 chaperone protein kinase targeting subunit p50Cdc37, Hsp90 co chaperone Cdc37, p50, p50Cdc37.

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Quotti Tubi, et al. (2013) J Hematol Oncol. 6: 78.;; Manni S., et al. (2012) Clin Cancer Res. 18: 1888-900.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human CDC37 (1-378aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of CDC37 in Balb/3T3 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human CDC37 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).

WB Comment and Pic :

The cell line and tissue lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CDC37 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1. : Jurkat cell lysate ;;Lane 2. : A431 cell lysate ;;Lane 3. : K562 cell lysate ;;Lane 4. : LnCap cell lysate ;;Lane 5. : SW480 cell lysate ;;Lane 6. : HeLa cell lysate ;;Lane 7. : MCF7 cell lysate ;;Lane 8. : 293T cell lysate

Reacts With :

Human

Clone Number :

AT3G7

Ab Usage :

The antibody has been tested by ELISA, Western blot analysis and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Cell Cycle

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q16543

Internal Search Terms :

CDC37, Cell division cycle 37 homolog, P50CDC37, CDC37, Cell division cycle 37 homolog, Cell division cycle 37 homolog S cerevisiae hypothetical protein CDC37, CDC 37, CDC37 cell division cycle 37 homolog, Cdc37 homolog, CDC37 protein, Hsp90 chaperone protein kinase targeting subunit, Hsp90 chaperone protein kinase targeting subunit p50Cdc37, Hsp90 co chaperone Cdc37, p50, p50Cdc37.,ATGA0428-10ug,ATGA0428-20ug,ATGA0428-50ug,ATGA0428-100ug,ATGA0428-250ug,ATGA0428-500ug,ATGA0428-1mg,ATGA0428-10,ATGA0428-20,ATGA0428-50,ATGA0428-100,ATGA0428-250,ATGA0428-500,ATGA0428-1

more info or order :

NKMAX product webpage