Human Pontin/RUVBL1 antibody | NKMAX ATGA0423 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human Pontin/RUVBL1 antibody

catalog :

ATGA0423

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT1D6

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human Pontin/RUVBL1 antibody

Catalog number (SKU) :

ATGA0423

NCBI :

NP_003698

Description :

RuVBL1, also known as TIP49A, is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This complex may be required for the activation of transcriptional programs associated with oncogene and proto oncogene mediated growth induction, tumor suppressor mediated growth arrest.

Alternative Names :

49 kDa TATA box-binding protein-interacting protein, 49 kDa TBP-interacting protein, 54 kDa erythrocyte cytosolic protein, ECP-54, INO80 complex subunit H, INO80H, NMP 238, Nuclear matrix protein 238, Pontin 52, RuvB like AAA ATPase 1, RuvB-like 1, RVB1, TAP54-alpha, TIH1, TIP49a, TIP60-associated protein 54-alpha

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Jha S., et al. (2009) Mol Cell. 34(5): 521-33.;; Haurie V., et al. (2009) Hepatology. 50(6): 1871-83.;;

Abs Host :

Mouse

Isotype :

IgG2a kappa

Immunogen :

Recombinant human RuVBL1 (1-456aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of RuVBL in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human RuVBL antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). {ATGA0423-IF1b.jpg}

WB Comment and Pic :

The cell lysate (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human RuVBL1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1 : Raji cell lysate

Reacts With :

Human

Clone Number :

AT1D6

Ab Usage :

The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9Y265

Internal Search Terms :

49 kDa TATA box-binding protein-interacting protein, 49 kDa TBP-interacting protein, 54 kDa erythrocyte cytosolic protein, ECP 54, ECP54, ECP-54, INO80 complex subunit H, INO80H, NMP 238, NMP238, NMP-238, Nuclear matrix protein 238, PONTIN, Pontin 52, Pontin52, Pontin-52, RuvB like AAA ATPase 1, RuVBL 1, RuVBL1, RuVBL-1, RuvB-like 1, RVB1, TAP54-alpha, TIH1, TIP 49, TIP49, TIP-49, TIP49a, TIP60-associated protein 54-alpha, ATGA0423-10ug, ATGA0423-20ug, ATGA0423-50ug, ATGA0423-100ug, ATGA0423-250ug, ATGA0423-500ug, ATGA0423-1mg, ATGA0423-010, ATGA0423-020, ATGA0423-050, ATGA0423-100, ATGA0423-250, ATGA0423-500, ATGA0423-01M

more info or order :

NKMAX product webpage