Human QPRT antibody | NKMAX ATGA0412 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human QPRT antibody

catalog :

ATGA0412

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT24C4

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human QPRT antibody

Catalog number (SKU) :

ATGA0412

NCBI :

NP_055113

Description :

Quinolinate phosphoribosyltransferase, also known as QPRT, is a major enzyme in the catabolism of quinolinate. It is an intermediate in the tryptophannicotinamide adenine dinucleotide (NAD) pathway, leading to the production of nicotinic acid, carbon dioxide and pyrophosphate. Elevation of QPRT levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

Alternative Names :

Nicotinate nucleotide pyrophosphorylase (carboxylating), Nicotinate nucleotide pyrophosphorylase carboxylating, Quinolinate phosphoribosyltransferase, QPRTase, QAPRTase

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Cao H., et al. (2002) Biochemistry. 41(10): 3520-8.;; Liu H., et al. (2007) J Mol Biol. 373(3): 755-63.;;

Abs Host :

Mouse

Isotype :

IgG2a kappa

Immunogen :

Recombinant human QPRT (1-297aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of QPRT in Hep3B cells. The cell was stained with ATGA0412 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human QPRT antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;; Lane 1 : HepG2 cell lysate;; Lane 2 : K562 cell lysate

Reacts With :

Human

Clone Number :

AT24C4

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Neuroscience

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q15274

Internal Search Terms :

QPRT,ATGA0412-10ug,ATGA0412-20ug,ATGA0412-50ug,ATGA0412-100ug,ATGA0412-250ug,ATGA0412-500ug,ATGA0412-1mg,ATGA0412-10,ATGA0412-20,ATGA0412-50,ATGA0412-100,ATGA0412-250,ATGA0412-500,ATGA0412-1

more info or order :

NKMAX product webpage