Human NDRG1 antibody | NKMAX ATGA0401 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human NDRG1 antibody

catalog :

ATGA0401

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT11G4

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human NDRG1 antibody

Catalog number (SKU) :

ATGA0401

NCBI :

NP_006087

Description :

N-myc downstream regulated gene (NDRG) -1 is one of 4 members of the NDRG alpha/beta-hydrolase family. This protein is classified in databases as a tumor suppressor and heavy metal-response protein. Its functions include cell-cycle regulation, cellular differentiation, apoptosis, hypoxia response and metal-ion sensing. Mutation in the NDRG1 gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom (HMSNL), a severe autosomal recessive form of Charcot-Marie-Tooth (CMT) disease.

Alternative Names :

N-myc downstream regulated 1, CAP43, CMT4D, DRG1, GC4, HMSNL, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5, N-myc downstream regulated 1 TDD5, 42 kDa, anti-GC4, cmt4d, Differentiation related gene1 protein, Drg 1, hmsnl, Human mRNA for RTP complete cds, NDRG1, tdds, N myc downstream regulated gene 1, N myc downstream regulated gene 1 protein, Ndr 1, ndr1, NDRG 1, NDRG1 protein, Protein nickel specific induction protein, Nickel specific induction protein Cap43, nmsl, Nmyc downstream regulated, reduced in tumor, reducin, Nmyc downstream regulated gene1, Nmyc downstream regulated gene1 protein, Protein regulated by oxygen 1, Protein regulated by oxygen1, proxy1, Reducing agents and tunicamycin responsive protein, tunicamycin-responsive protein

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Van Belzen N., et al. (1997) Lab Invest. 77(1): 85-92.;; Kokame K., et al. (1997) J Biol Chem. 271(47): 29659-29665. ;; Zhang J., et al. (2008) Gene. 417(1-2): 5-12.;; Kachhap SK., et al. (2007) PLoS ONE. 2(9): e844.;;

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human NDRG1 (1-394aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of NDRG1 in HeLa cells. The cell was stained with ATGA0401 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human NDRG1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;; Lane 1. : LnCaP cell lysate ;; Lane 2. : HeLa cell lysate ;;Lane 3. : PC3 cell lysate ;; Lane 4. : Hep3B cell lysate ;;Lane 5. : HT1080 cell lysate ;;Lane 6. : Jurkat cell lysate ;;Lane 7. : SW480 cell lysate

Reacts With :

Human

Clone Number :

AT11G4

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Neuroscience

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q92597

Internal Search Terms :

NDRG1,ATGA0401-10ug,ATGA0401-20ug,ATGA0401-50ug,ATGA0401-100ug,ATGA0401-250ug,ATGA0401-500ug,ATGA0401-1mg,ATGA0401-10,ATGA0401-20,ATGA0401-50,ATGA0401-100,ATGA0401-250,ATGA0401-500,ATGA0401-1

more info or order :

NKMAX product webpage