Human HINT2 antibody | NKMAX ATGA0378 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human HINT2 antibody

catalog :

ATGA0378

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT5B10

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human HINT2 antibody

Catalog number (SKU) :

ATGA0378

NCBI :

NP_115982

Description :

Histidine triad nucleotide binding protein 2 (HINT2) is a mitochondrial protein. This protein is an AMP-lysine hydrolase and phosphoamidase and may contribute to tumor suppression. This protein is a member of the HIT superfamily and Hint subfamily, which are characterized as nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides. HINT2 regulates steroidogenesis through calcium-dependent and calcium-independent signalling pathways that may serve to maintain a favorable mitochondrial potential. Its role in calcium homeostasis may also contribute to its proapoptotic function in hepatocytes and other non-steroidogenic cells, though the exact mechanism remains unclear.

Alternative Names :

Histidine triad nucleotide-binding protein 2, HIT-17

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Maize KM., et al. (2013) The FEBS journal. 280(14): 3389-3398.;; Lenglet S., et al. (2008) Endocrinology. 149(11): 5461-5469.;; Martin J., et al. (2006) Gastroenterology. 130(7): 2179-2188.;; Lee LR., et al. (2013) Cancer prevention research. 6(7): 731-743.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human HINT2 (18-163aa) purified from E. coli

Applications :

ELISA,WB

WB Comment and Pic :

The recombinant human HINT2 (50ng) and Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human HINT2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1. : HINT2 Recombinant protein ;;Lane 2. : HepG2 cell lysate ;;Lane 3. : U87MG cell lysate

Reacts With :

Human

Clone Number :

AT5B10

Ab Usage :

The antibody has been tested by ELISA, Western blot analysis and Flow cytometry to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Signal Transduction

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9BX68

Internal Search Terms :

HINT2, Histidine triad nucleotide-binding protein 2, HIT-17,ATGA0378-10ug,ATGA0378-20ug,ATGA0378-50ug,ATGA0378-100ug,ATGA0378-250ug,ATGA0378-500ug,ATGA0378-1mg,ATGA0378-10,ATGA0378-20,ATGA0378-50,ATGA0378-100,ATGA0378-250,ATGA0378-500,ATGA0378-1

more info or order :

NKMAX product webpage