Human VHR/DUSP3 antibody | NKMAX ATGA0374 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human VHR/DUSP3 antibody

catalog :

ATGA0374

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT9E6

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human VHR/DUSP3 antibody

Catalog number (SKU) :

ATGA0374

NCBI :

NP_004081

Description :

DUSP3, also known as Dual specificity protein phosphatase 3, is inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

Alternative Names :

Dual specificity protein phosphatase 3, VHR, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase, Vaccinia virus phosphatase VH1-related

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Sun H. (1998) Mol Biol. 84: 307-318.;; Folander K., et al. (1995) Genomics. 23(1): 295-296.

Abs Host :

Mouse

Isotype :

IgG2b kappa

Immunogen :

Recombinant human DUSP3 (1-185aa) purified from E. coli

Applications :

ELISA, WB

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human VHR antibody (1:3000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: HeLa cell lysate;;Lane 2.: HepG2 cell lysate;;Lane 3.: Jurkat cell lysate;;Lane 4.: MCF7 cell lysate;;Lane 5.: 293T cell lysate;;Lane 6.: U87MG cell lysate;;Lane 7.: K562 cell lysate

Reacts With :

Human

Clone Number :

AT9E6

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Signal Transduction

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

P51452

Internal Search Terms :

VHR,ATGA0374-10ug,ATGA0374-20ug,ATGA0374-50ug,ATGA0374-100ug,ATGA0374-250ug,ATGA0374-500ug,ATGA0374-1mg,ATGA0374-10,ATGA0374-20,ATGA0374-50,ATGA0374-100,ATGA0374-250,ATGA0374-500,ATGA0374-1

more info or order :

NKMAX product webpage