Human RANBP3 antibody | NKMAX ATGA0310 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human RANBP3 antibody

catalog :

ATGA0310

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT12E11

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human RANBP3 antibody

Catalog number (SKU) :

ATGA0310

NCBI :

NP_015559

Description :

The GTPase Ran is a small protein that belongs to the RAS protein superfamily and is found associated with the nuclear membrane. Ran GTPase is essential for mRNA processing, nuclear transport, cell cycle control, mitotic spindle assembly, and postmitotic nuclear re-assembly and nuclear architecture maintenance. Ran binding proteins (RanBPs) belong to a family of proteins that bind Ran GTPase and help to stimulate its GTPase activity. Members of the RanBP family show weak similarity to importin beta, a protein involved in the transport of proteins to the nuclear membrane. Recently it has been shown that RanBP3 function is regulated by the Ras/ERK/RSK and PI3K/Akt signaling pathway. This finding has provided a link between nuclear transport, cell signaling, and cell fate.

Alternative Names :

Ran-binding protein 3 isoform RANBP3-b, RAN binding protein 3

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Englmeier L , (2001) EMBO Rep. 2(10):926-32.;; Mueller L, (1998) FEBS Lett. 427(3):330-6.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human RANBP3 (235-445aa) purified from E. coli

Applications :

ELISA, WB

WB Comment and Pic :

The cell lysates of Jurkat (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human RANBP3 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

AT12E11

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Cell Cycle

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9H6Z4

Internal Search Terms :

RANBP3, Ran-binding protein 3 isoform RANBP3-b, RAN binding protein 3,ATGA0310-10ug,ATGA0310-20ug,ATGA0310-50ug,ATGA0310-100ug,ATGA0310-250ug,ATGA0310-500ug,ATGA0310-1mg,ATGA0310-10,ATGA0310-20,ATGA0310-50,ATGA0310-100,ATGA0310-250,ATGA0310-500,ATGA0310-1

more info or order :

NKMAX product webpage