Human STOM antibody | NKMAX ATGA0291 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human STOM antibody

catalog :

ATGA0291

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT33F5

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human STOM antibody

Catalog number (SKU) :

ATGA0291

NCBI :

NP_004090

Description :

STOM (stomatin) is a member of a highly conserved family of integral membrane proteins. This protein localizes to the cell membrane of red blood cells and other cell types, where it may regulate ion channels and transporters. Loss of localization of STOM is associated with hereditary stomatocytosis, a form of hemolytic anemia. Although the wide distribution of stomatin and its constitutive expression suggest an important role for this protein in cell biology, perhaps as a house-keeping component, its function remains undetermined. The massive presence of stomatin in membrane-protruding folds and extensions suggests a possible structural role for this protein in the formation of these structures and/or the anchorage to the actin cytoskeleton.

Alternative Names :

Erythrocyte band 7 integral membrane protein isoform a, BND7, EPB7, EPB72

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hiebl-Dirschmied CM., et al. (1991) Biochim Biophys Acta 1090 (1): 123-4.;; Stewart GW (1997) J. Biol. Chem. 29 (2): 271-4.;; Entrez Gene: STOM stomatin.;;

Abs Host :

Mouse

Isotype :

IgG2b kappa

Immunogen :

Recombinant human STOM (55-288aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of STOM in HeLa cells. The cell was stained with ATGA0291 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The cell lysate of HeLa (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human STOM antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. The cell lysates (20ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human STOM antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;; Lane 1.: 293T cell lysate;; Lane 2.: STOM Transfected 293T cell lysate {ATGA0291-WB2.jpg}

Reacts With :

Human

Clone Number :

AT33F5

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Neuroscience

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

P27105

Internal Search Terms :

STOM,ATGA0291-10ug,ATGA0291-20ug,ATGA0291-50ug,ATGA0291-100ug,ATGA0291-250ug,ATGA0291-500ug,ATGA0291-1mg,ATGA0291-10,ATGA0291-20,ATGA0291-50,ATGA0291-100,ATGA0291-250,ATGA0291-500,ATGA0291-1

more info or order :

NKMAX product webpage