Human ING2 antibody | NKMAX ATGA0290 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human ING2 antibody

catalog :

ATGA0290

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT39E5

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human ING2 antibody

Catalog number (SKU) :

ATGA0290

NCBI :

NP_001555

Description :

ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.

Alternative Names :

inhibitor of growth protein 2, ING1L, P33ing2

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Entrez Gene: ING2 inhibitor of growth family, member 2.;; Shimada Y., et al. (1999) Cytogenet Cell Genet 83 (3-4): 232-5.;; Nagashima M., et al. (2001) Proc. Natl. Acad. Sci. U.S.A. 98: 9671-9676.;; Gozani O., et al. (2003) Cell 114: 99-111.;;

Abs Host :

Mouse

Isotype :

IgG1b kappa

Immunogen :

Recombinant human ING2 (1-280aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of ING2 in Hep3B cells. The cell was stained with ATGA0290 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The cell lysate of HeLa (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human ING2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

AT39E5

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9H160

Internal Search Terms :

ING2,ATGA0290-10ug,ATGA0290-20ug,ATGA0290-50ug,ATGA0290-100ug,ATGA0290-250ug,ATGA0290-500ug,ATGA0290-1mg,ATGA0290-10,ATGA0290-20,ATGA0290-50,ATGA0290-100,ATGA0290-250,ATGA0290-500,ATGA0290-1

more info or order :

NKMAX product webpage