Human Snail antibody | NKMAX ATGA0288 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human Snail antibody

catalog :

ATGA0288

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT2D5

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human Snail antibody

Catalog number (SKU) :

ATGA0288

NCBI :

NP_005976

Description :

SNAI1, also known as Snail homolog 1, is involved in the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. This protein binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription. Both SNAI1 and SLUG belong to the snail C2H2-type zinc-finger protein family. SLUG is a transcriptional repressor, involved in the generation and migration of neural crest cells. SNAI1 is expressed in mesenchymal, epithelial cell lines and highest expression in kidney.

Alternative Names :

Snail homolog 1, dJ710H13.1, SLuGH2, SNA, SNAH, SNAIL, SNAIL1

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Batlle. E., et al. (2000) Nat Cell Biol 2: 84-89.;; Yook. J.I., et al. (2005) J Biol Chem 280: 11740-11748.;; Twigg. S.R. and Wilkie. A.O.M. (1999) Hum Genet 105: 320-326.;;

Abs Host :

Mouse

Isotype :

IgG2b kappa

Immunogen :

Recombinant human SNAI1 (1-264aa) purified from E. coli

Applications :

ELISA, WB

WB Comment and Pic :

The cell lysate of A549 (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SNAI1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

AT2D5

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

O95863

Internal Search Terms :

Snail, SNAI1,ATGA0288-10ug,ATGA0288-20ug,ATGA0288-50ug,ATGA0288-100ug,ATGA0288-250ug,ATGA0288-500ug,ATGA0288-1mg,ATGA0288-10,ATGA0288-20,ATGA0288-50,ATGA0288-100,ATGA0288-250,ATGA0288-500,ATGA0288-1

more info or order :

NKMAX product webpage