Human SORD antibody | NKMAX ATGA0283 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human SORD antibody

catalog :

ATGA0283

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT10F4

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human SORD antibody

Catalog number (SKU) :

ATGA0283

NCBI :

AAH25295

Description :

SORD, also known as sorbitol dehydrogenase, is a 357 amino acid protein of the zinc-containing alcohol dehydrogenase family. It is widely expressed with highest expression in kidney, lens of the eye and malignant prostate tissue. SORD enzymatically catalyzes the zinc-dependent interconversion of polyols, such as sorbitol and xylitol, to their respective ketoses. SORD deficiency may be associated with diabetic complications such as cataracts and microvascular problems.

Alternative Names :

Sorbitol dehydrogenase, Sorbitol dehydrogenase L iditol 2 dehydrogenase, SDH, SORD, SORD 1, SORD1

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Frenette. G., et al. (2006) J Androl 27: 233-239. ;; Szabo. Z., et al. (2010) Oncol Rep 23: 1233-1239.;; Lanaspa. M.A., et al. (2009) J Biol Chem 284: 19974-19981.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human SORD (1-357aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of SORD in Hep3B cells. The cell was stained with ATGA0283 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The recombinant protein (20ng) and cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SORD antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;; Lane 1.: SORD recombinant protein ;; Lane 2.: Jurkat cell lysate;;Lane 3.: HeLa cell lysate;;

Reacts With :

Human

Clone Number :

AT10F4

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Metabolism

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q00796

Internal Search Terms :

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more info or order :

NKMAX product webpage