Human REXO2 antibody | NKMAX ATGA0269 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human REXO2 antibody

catalog :

ATGA0269

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT59D9

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human REXO2 antibody

Catalog number (SKU) :

ATGA0269

NCBI :

NP_056338

Description :

REX2, RNA exonuclease 2 homolog (S. cerevisiae), also known as REXO2, is an enzyme which in humans is encoded by the REXO2 gene. Nucleases are components of DNA and RNA metabolism that carry out functions in DNA repair that also may be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process, replication, and recombination and in RNA processing and degradation. SFN is a homolog of Orn, a 3-prime-to-5-prime exoribonuclease of E. coli that attacks the free 3-prime hydroxyl group on single-stranded RNA, releasing 5-prime mono-nucleotides in a sequential manner.

Alternative Names :

Oligoribonuclease mitochondrial, Oligoribonuclease, mitochondrial, REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, REX2, RFN, SFN

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Entrez Gene: REXO2 REX2, RNA exonuclease 2 homolog (S. cerevisiae);; Lai, CH., et al. (2000) Genome Res 10(5): 703-13;; Nguyen, LH., et al. (2000) J.Biol.Chem 275(34): 25900-6

Abs Host :

Mouse

Isotype :

IgG2b kappa

Immunogen :

Recombinant human REXO 2 (26-237aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of REXO2 in 293T cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human REXO2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). {ATGA0269-IF1b.jpg} ICC/IF analysis of REXO2 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human REXO2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green). {ATGA0269-IF2a.jpg} {ATGA0269-IF2b.jpg}

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human REXO2 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1. : SW480 cell lysate ;;Lane 2. : HeLa cell lysate ;;Lane 3. : 293T cell lysate ;;Lane 4. : Jurkat cell lyate ;;Lane 5. : K562 cell lysate ;;Lane 6. : NIH3T3 cell lysate

Reacts With :

Human

Clone Number :

AT59D9

Ab Usage :

The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9Y3B8

Internal Search Terms :

REXO2, Oligoribonuclease mitochondrial, Oligoribonuclease, mitochondrial, REX2, RNA exonuclease 2 homolog (S. cerevisiae), CGI-114, REX2, RFN, SFN,ATGA0269-10ug,ATGA0269-20ug,ATGA0269-50ug,ATGA0269-100ug,ATGA0269-250ug,ATGA0269-500ug,ATGA0269-1mg,ATGA0269-10,ATGA0269-20,ATGA0269-50,ATGA0269-100,ATGA0269-250,ATGA0269-500,ATGA0269-1

more info or order :

NKMAX product webpage