Human MFAP4 antibody | NKMAX ATGA0268 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human MFAP4 antibody

catalog :

ATGA0268

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT12D11

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human MFAP4 antibody

Catalog number (SKU) :

ATGA0268

NCBI :

NP_002395

Description :

Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Also, MFAP4 play an important role in calcium-dependent cell adhesion or intercellular interactions. These structural features of MFAP4 suggest that it is an extracellular matrix protein involved in cell adhesion or intercellular interactions.

Alternative Names :

microfibrillar-associated protein 4, microfibrillar-associated protein 4, Microfibril associated glycoprotein 4, Microfibril-associated glycoprotein 4

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Zhao, Z., et al. (1995) Hum Mol Genet 4(4): 589-97.;; Kasamatsu, S., et al. (2011) Sci Rep 1:164.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human MFAP4 (22-255aa) purified from E. coli

Applications :

ELISA,WB

WB Comment and Pic :

The tissue lysate of lung (30ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MFAP4 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

AT12D11

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Signal Transduction

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

P55083

Internal Search Terms :

MFAP4,ATGA0268-10ug,ATGA0268-20ug,ATGA0268-50ug,ATGA0268-100ug,ATGA0268-250ug,ATGA0268-500ug,ATGA0268-1mg,ATGA0268-10,ATGA0268-20,ATGA0268-50,ATGA0268-100,ATGA0268-250,ATGA0268-500,ATGA0268-1

more info or order :

NKMAX product webpage