Human CIAO1 antibody | NKMAX ATGA0261 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human CIAO1 antibody

catalog :

ATGA0261

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT6C9

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human CIAO1 antibody

Catalog number (SKU) :

ATGA0261

NCBI :

NP_004795

Description :

CIAO1 is a essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. It is a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. CIAO1 seems to specifically modulate the transactivation activity of WT1 and may function to regulate the physiological functions of WT1 in cell growth and differentiation. As part of the mitotic spindle-associated MMXD complex, it may play a role in chromosome segregation.

Alternative Names :

Probable cytosolic iron-sulfur protein assembly protein CIAO1, CIA1, WDR39

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Johnstone, RW., et al. (1998) J Biol Chem 273(18): 10880-7.;; Srinivasan, V., et al. (2007) Structure 15: 1246-1257.;; Ito, S., et al. (2010) Mol Cell 39: 632-640.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human CIAO1 (1-339aa) purified from E. coli

Applications :

ELISA, WB

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CIAO1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1.: Jurkat cell lysate The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CIAO1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ;;Lane 1.: 293T cell lysate ;;Lane 2.: CIAO1 transfected 293T cell lysate {2004010217332740.jpg}

Reacts With :

Human

Clone Number :

AT6C9

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

O76071

Internal Search Terms :

CIAO1, Probable cytosolic iron-sulfur protein assembly protein CIAO1, CIA1, WDR39,ATGA0261-10ug,ATGA0261-20ug,ATGA0261-50ug,ATGA0261-100ug,ATGA0261-250ug,ATGA0261-500ug,ATGA0261-1mg,ATGA0261-10,ATGA0261-20,ATGA0261-50,ATGA0261-100,ATGA0261-250,ATGA0261-500,ATGA0261-1

more info or order :

NKMAX product webpage