Human KLF7 antibody | NKMAX ATGA0256 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human KLF7 antibody

catalog :

ATGA0256

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT3G3

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human KLF7 antibody

Catalog number (SKU) :

ATGA0256

NCBI :

NP_003700

Description :

KLK7 is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation, survival and the development of nervous systems. and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. KLF7 is binds specifically to an Ikaros core binding element that is crucial for in vivo NTRK1/TrkA enhancer function. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.

Alternative Names :

Kruppel-like factor 7, uKLF

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Matsumoto, N., et al. (1998) J Biol Chem 273(43): 28229-37.;; Kanazawa, A., et al. (2005) Diabetologia 48(7): 1315-22.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human KLF7 (1-302aa) purified from E. coli

Applications :

ELISA,WB

WB Comment and Pic :

The tissue lysate of mouse brain (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KLF7 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

AT3G3

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

O75840

Internal Search Terms :

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more info or order :

NKMAX product webpage