Human SNTA1 antibody | NKMAX ATGA0254 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human SNTA1 antibody

catalog :

ATGA0254

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT1E1

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human SNTA1 antibody

Catalog number (SKU) :

ATGA0254

NCBI :

NP_003089

Description :

SNTA1 (Syntrophin alpha 1) is 505 amino acid protein. SNTA1 is adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. It may link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. SNTA1 plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Defects of SNTA1 are the cause of long QT syndrome type 12 (LQT12).

Alternative Names :

Syntrophin alpha 1, Syntrophin, alpha 1, dJ1187J4.5, LQT12, SNT1, TACIP1

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wu, G., et al. (2008) Circ Arrhythm Electrophysiol 1: 193-201.;; Ahn, A.H., et al. (1996) J Biol Chem 271(5): 2724-30.;; Yang, B., et al (1995) J Biol Chem 270(10): 4975-8.

Abs Host :

Mouse

Isotype :

IgG2b kappa

Immunogen :

Recombinant human SNTA1 (1-505aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF

IF Comment And Pic :

ICC/IF analysis of SNTA1 in HeLa cells. The cell was stained with ATGA0254 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The cell lysate of HepG2 (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SNTA1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

AT1E1

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Cytoskeleton

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-A affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q13424

Internal Search Terms :

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more info or order :

NKMAX product webpage