Human CNDP2/CPGL antibody | NKMAX ATGA0236 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human CNDP2/CPGL antibody

catalog :

ATGA0236

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT15E5

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human CNDP2/CPGL antibody

Catalog number (SKU) :

ATGA0236

NCBI :

NP_060705

Description :

CNDP2, known as tissue carnosinase and peptidase A, is a nonspecific dipeptidase rather than a selective carnosinase and is a secreted peptidase homologous to M20 peptidases. Also known as glutamate carboxypeptidase-like protein 1 (CPGL), CNDP2 is ubiquitously expressed throughout human tissue. CNDP2 Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly and may be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells.

Alternative Names :

Cytosolic non-specific dipeptidase, CN2, CPGL, HsT2298, PEPA

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Zhang, P., et al. (2006) Cancer res 12: 6617-6625;;Kaur, H., et al. (2009) J.Biol.Chem 284: 14493-14502;; Licker, V., et al. (2012) J proteomics 375(15): 4656-67

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human CNDP2 (1-475aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of CNDP2/CPGL in HeLa cells. The cell was stained with ATGA0236 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The tissue lysate of mouse kidney (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CNDP2/CPGL antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.The lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CNDP2/CPGL antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1.: Mouse liver tissue lysate;;Lane 2.: HepG2 cell lysate;;{ATGA0236-WB2.jpg}

Reacts With :

Human

Clone Number :

AT15E5

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Enzymes & Proteases, Ubiquitination

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-G affinity chromatography

Product Type Name :

Monoclonal antibody

UniProt No. :

Q96KP4

Internal Search Terms :

CNDP2, CPGL,ATGA0236-10ug,ATGA0236-20ug,ATGA0236-50ug,ATGA0236-100ug,ATGA0236-250ug,ATGA0236-500ug,ATGA0236-1mg,ATGA0236-10,ATGA0236-20,ATGA0236-50,ATGA0236-100,ATGA0236-250,ATGA0236-500,ATGA0236-1

more info or order :

NKMAX product webpage