Human CMBL antibody | NKMAX ATGA0233 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human CMBL antibody

catalog :

ATGA0233

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT2B11

reactivity :

human

application :

western blot, ELISA

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human CMBL antibody

Catalog number (SKU) :

ATGA0233

NCBI :

NP_620164

Description :

CMBL (carboxymethylenebutenolidase homolog) is a 245 amino acid cytosolic protein and cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL is the human homolog of Pseudomonas dienelactone hydrolase, a protein that participates in the bacterial halocatechol degradation pathway. That is ubiquitously expressed with high expression in liver, colon, kidney and small intestine, where it acts as a bioactivating enzyme for a prodrug type angiotensin II type 1 receptor antagonist known as olmesartan medoxomil. CMBL is inhibited by p-chloromercuribenzoate (PCMB).

Alternative Names :

Carboxymethylenebutenolidase homolog

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ishizuka T, et al. (Apr 2010). J Biol Chem. 16285(16):11892-902. ;; Yang X, et al. (Mar 2010). J Proteome Res. 59(3):1402-15.

Abs Host :

Mouse

Isotype :

IgG2a kappa

Immunogen :

Recombinant human CMBL (1-245aa) purified from E. coli

Applications :

ELISA,WB

WB Comment and Pic :

The cell lysates of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CMBL antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

AT2B11

Ab Usage :

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Metabolism

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-G affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q96DG6

Internal Search Terms :

CMBL,ATGA0233-10ug,ATGA0233-20ug,ATGA0233-50ug,ATGA0233-100ug,ATGA0233-250ug,ATGA0233-500ug,ATGA0233-1mg,ATGA0233-10,ATGA0233-20,ATGA0233-50,ATGA0233-100,ATGA0233-250,ATGA0233-500,ATGA0233-1

more info or order :

NKMAX product webpage