Human KCTD15 antibody | NKMAX ATGA0121 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human KCTD15 antibody

catalog :

ATGA0121

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AT2B11

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, FACS

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human KCTD15 antibody

Catalog number (SKU) :

ATGA0121

NCBI :

NP_076981

Description :

KCTD15 (Potassium channel tetramerisation domain containing 15, also known as BTB/POZ domain-containing protein KCTD15) is protein that in humans is encoded by the KCTD15 gene. KCTD15 is expressed at high level in brain and hypothalamus. The potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels.

Alternative Names :

BTB/POZ domain-containing protein KCTD15, MGC25497, MGC2628

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Elks CE, et al. (2010) PLoS Med. 7(5): e1000284.;; Strausberg RL, et al. (2002) Proc. Natl. Acad. Sci. U.S.A, 99(26): 16899-903.;; Willer CJ, et al. (2010) Nat. Genet, 41(1): 24-34.

Abs Host :

Mouse

Isotype :

IgG2b kappa

Immunogen :

Recombinant human KCTD15(1-159aa) purified from E. coli

Applications :

ELISA,WB,ICC/IF,FACS

IF Comment And Pic :

ICC/IF analysis of KCTD15 in HeLa cells. The cell was stained with ATGA0121 (1:100). The secondary antibody (green) was used Alexa Fluor 488.

WB Comment and Pic :

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KCTD15 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;;Lane 1 : HeLa cell lysate;;Lane 2 : NIH/3T3 cell lysate;;Lane 3 : K562 cell lysate

Reacts With :

Human

Clone Number :

AT2B11

Ab Usage :

The antibody has been tested by ELISA, Western blot, ICC/IF and FACS analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

FACS Comment and Pic :

Flow cytometry analysis of KCTD15 in HeLa cells. The cell was stained with ATGA0121 at 2-5ug for 1x10^6cells (red). A Goat anti mouse IgG (Alexa fluor 488) was used as the secondary antibody. Mouse monoclonal IgG was used as the isotype control (dark gray), cells without incubation with primary and secondary antibody was used as the negative control (light gray).

Antigen Species :

Human

Gene Category :

Neuroscience

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-G affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q96SI1

Internal Search Terms :

KCTD15,ATGA0121-10ug,ATGA0121-20ug,ATGA0121-50ug,ATGA0121-100ug,ATGA0121-250ug,ATGA0121-500ug,ATGA0121-1mg,ATGA0121-10,ATGA0121-20,ATGA0121-50,ATGA0121-100,ATGA0121-250,ATGA0121-500,ATGA0121-1

more info or order :

NKMAX product webpage