Human Folate hydrolase 1/FOLH1 antibody | NKMAX APS0819 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human Folate hydrolase 1/FOLH1 antibody

catalog :

APS0819

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

k1H7

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human Folate hydrolase 1/FOLH1 antibody

Catalog number (SKU) :

APS0819

NCBI :

NP_001014986

Description :

Prostate-specific membrane antigen (PSMA) is a 100-120 kDa type II transmembrane glycoprotein that is a glutamate-preferring carboxy-peptidase. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. PSMA is highly expressed in prostate secretory-acinar epithelium, in some benign extraprostatic epithelial cells from breast, duodenum, and kidney tissues, and in prostate cancer.

Alternative Names :

Glutamate carboxypeptidase 2, Cell growth-inhibiting gene 27 protein, Folylpoly-gamma-glutamate carboxypeptidase, FGCP, Glutamate carboxypeptidase II, GCPII, Membrane glutamate carboxypeptidase, mGCP, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Prostate-specific membrane antigen, PSM, PSMA, Pteroylpoly-gamma-glutamate carboxypeptidase, FOLH, Naalad1

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Rajasekaran SA, et al., (2008) Mol Cancer Ther 7(7):2142-2151.;; Polly D.G, et al., (2005) Int J Cancer 116(3):415-421.;; Susan F.S, et al., (2005) Expert Opin Ther Targets 9(3):561-570.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human PSMA (117-351aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of PSMA in LNCaP cells. The cell was stained with APS0819 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The Cell lysate of LNCaP(30ug) was resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human PSMA (1:1,000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

k1H7

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Cancer

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-G affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q04609

Internal Search Terms :

PSMA, FOLH1, NAALADase I,APS0819-10ug,APS0819-20ug,APS0819-50ug,APS0819-100ug,APS0819-250ug,APS0819-500ug,APS0819-1mg,APS0819-10,APS0819-20,APS0819-50,APS0819-100,APS0819-250,APS0819-500,APS0819-1

more info or order :

NKMAX product webpage