Human PDCD12 antibody | NKMAX APD0912 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human PDCD12 antibody

catalog :

APD0912

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3G4

reactivity :

human

application :

western blot, ELISA, immunohistochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human PDCD12 antibody

Catalog number (SKU) :

APD0912

NCBI :

NP_065104

Description :

PDCD12 (Programmed cell death 12), also referred to as AVEN, represents a new class of cell death regulator. PDCD12 is a conserved intracellular membrane protein that blocks apoptosis impeded by Apaf-1 mediated caspase activation. Bcl-2 and BAD also interact with PDCD12 to prevent apoptosis. It is expressed in a wide variety of normal tissues including heart, skeletal muscle, kidney, liver, testis, and diseases such as cancer

Alternative Names :

cell death regulator aven, apoptosis, caspase activation inhibitor, PDCD12, programmed cell death 12

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Figueroa B Jr, et al: (2004) Biotechnol Bioeng. 85(6), 589-600.;; Cheng EH, et al: (2000) Mol Cell. 6(1), 31-40.

Abs Host :

Mouse

Isotype :

IgG2a kappa

Immunogen :

Recombinant human PDCD12 (254-362aa) purified from E. coli

Applications :

ELISA,WB,IHC

WB Comment and Pic :

The tissue lysate of mouse kidney (50ug) was resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human PDCD12 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

3G4

Ab Usage :

The antibody has been tested by ELISA, Western blot and IHC analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

IHC Comment And Pic :

Paraffin embedded sections of human breast lobule tissue were incubated with anti-human PDCD12 (1:50) for 2 hours at room temperature. Antigen retrieval was performed in 0.1M sodium citrate buffer and detected using Diaminobenzidine (DAB)

Antigen Species :

Human

Gene Category :

Cancer

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-G affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

Q9NQS1

Internal Search Terms :

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more info or order :

NKMAX product webpage