Human CD158b2/KIR2DL3 antibody | NKMAX AKR3006 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human CD158b2/KIR2DL3 antibody

catalog :

AKR3006

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

190IIC311

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human CD158b2/KIR2DL3 antibody

Catalog number (SKU) :

AKR3006

NCBI :

NP_055326

Description :

Reacts with extracellular domain of the KIR2DL3, a member of the Killer cell immunoglobulin-liKe receptor(KIR) family. The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on human NK cells and a subset of human T cells which they are involved in recognition of either MHC class I molecules or unKnown ligand on target cells and inhibit cytotoxic activities.

Alternative Names :

Killer cell immunoglobulin like receptor, Two Ig domains and long cytoplasmic tail 3, Killer cell immunoglobulin-like receptor 2DL3, CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, NKAT2a, NKAT2b, Natural killer-associated transcript 2, NKAT-2, p58 natural killer cell receptor clone CL-6, p58 NK receptor CL-6, p58.2 MHC class-I-specific NK receptor, CD158B2, KIRCL23, p58

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Shin JS, et al., (1999) Hybridoma 18:521-527.;; Chwae YJ, et al., (2002) J Immunology 169:3726-3735.

Abs Host :

Mouse

Isotype :

IgG2a kappa

Immunogen :

Recombinant human KIR2DL3 (19-161aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of KIR2DL3 in HeLa cells. The cell was stained with AKR3006 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The recombinant proteins (50ng) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human KIR2DL3 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.;; Lane 1.: KIR2DL1 recombinant protein;; Lane 2.: KIR2DL3 recombinant protein;; Lane 3.: KIR2DS4 recombinant protein

Reacts With :

Human

Clone Number :

190IIC311

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Immunology

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-G affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

P43628

Internal Search Terms :

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more info or order :

NKMAX product webpage