protein

Recombinant mouse Adiponectin/Acrp30 protein

ADI0702

20 ug

80 USD

Recombinant mouse Adiponectin/Acrp30 protein

18-247aa

ADI0702

NP_033735

Adiponectin is an adipocyte specific secreted protein that circulates in the plasma. It is induced during adipocyte differentiation and its secretion is stimulated by insulin. Mouse adiponectin shares about 83% amino acid identity with that human. Adiponectin plays a role in various physiological processes such as energy homeostasis and obesity. Adiponectin is reduced in obese humans, and decreased level is associated with insulin resistance and hyperinsulinemia. Recombinant mouse adiponectin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

ADIPOQ, Acdc, Acrp30, Apm1, 30 kDa adipocyte complement-related protein, Adipocyte complement-related 30 kDa protein, Adipocyte C1q and collagen domain-containing protein, Adipocyte-specific protein

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Yokota. T. et al. (2000) Blood. 96:1723;; Yamauchi T. et al (2002) Nature Medicine.8(11):1288-1295;; Lu M. et al (2007) Mol Endocrinol. 59(2):207-16;;

> 90% by SDS-PAGE

SDS-PAGE

Mouse

Hormones & Cytokines

27.2 kDa (251aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

MGSSHHHHHH SSGLVPRGSH MEDDVTTTEE LAPALVPPPK GTCAGWMAGI PGHPGHNGTP GRDGRDGTPG EKGEKGDAGL LGPKGETGDV GMTGAEGPRG FPGTPGRKGE PGEAAYVYRS AFSVGLETRV TVPNVPIRFT KIFYNQQNHY DGSTGKFYCN IPGLYYFSYH ITVYMKDVKV SLFKKDKAVL FTYDQYQEKN VDQASGSVLL HLEVGDQVWL QVYGDGDHNG LYADNVNDST FTGFLLYHDT N

His-Tag

E.coli

Recombinant Protein

Q60994

Adiponectin, Acrp30, adipocyte complement-related protein, Acdc, GBP28, Acrp30, mAdiponectin, 18- 247aa, Mouse, His-tagged, Adiponectin, C1Q and collagen domain containing [Mus musculus],ADI0702-10ug,ADI0702-20ug,ADI0702-50ug,ADI0702-100ug,ADI0702-250ug,ADI0702-500ug,ADI0702-1mg,ADI0702-10,ADI0702-20,ADI0702-50,ADI0702-100,ADI0702-250,ADI0702-500,ADI0702-1

Jeon BT, et al. Adiponectin protects hippocampal neurons against kainic acid-induced excitotoxicity. (Brain Res Rev. 2009){https://pubmed.ncbi.nlm.nih.gov/19460404/};;Suzuki Y, et al. Chemerin is a novel regulator of lactogenesis in bovine mammary epithelial cells. (Biochem Biophys Res Commun. 2015){https://pubmed.ncbi.nlm.nih.gov/26342800/}