Human BMP-7 antibody | NKMAX ABM0615 product information

product summary

company name :

NKMAX

product type :

antibody

product name :

Human BMP-7 antibody

catalog :

ABM0615

quantity :

50 ul

price :

170 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4E7

reactivity :

human

application :

western blot, ELISA, immunocytochemistry

more info or order :

NKMAX product webpage

product information

Product Type :

Antibodies

Item Name :

Human BMP-7 antibody

Catalog number (SKU) :

ABM0615

NCBI :

NP_001710

Description :

BMP-7 (bone morphogenetic protein-7), also known as OP-1 (osteogenic protein-1), is a member of the transforming growth factorbeta (TGFbeta) superfamily. BMP-7 plays an essential role during ontogeny of the mammalian eye and kidney, also, is expressed in heart, lung, small intestine, limb bud and teeth. In addition, noggin, one of the soluble BMP antagonists, regulated the action of BMPs on mesenchymal precursor cells, partially through a feedback type of inhibition.

Alternative Names :

BMP 7, Bone morphogenetic protein 7, Eptotermin alfa, OP-1, Osteogenic protein 1

Concentration :

1mg/ml (determined by BCA assay)

Formulation :

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gregory KE., et al. (2005) J. Biol, Chem. 280, 27970-27980.;; Sampath Tk., et al. (1990) J. Biol. Chem. 265:13198-13205.;; Godin RE., et al. (1998) Development. 125:3473-3482.;; Groppe J., et al. (2002) Nature. 420:636-642.

Abs Host :

Mouse

Isotype :

IgG1 kappa

Immunogen :

Recombinant human BMP7 (293-431aa) purified from E. coli

Applications :

ELISA, WB, ICC/IF

IF Comment And Pic :

ICC/IF analysis of BMP7 in HeLa cells. The cell was stained with ABM0615 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).

WB Comment and Pic :

The extracts of mouse kidney (MK) and rat heart (RH) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human BMP7 antibody (1:1,000). Protein was visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Reacts With :

Human

Clone Number :

4E7

Ab Usage :

The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Conjugation :

Unconjugated

Clonality Mono VS Poly :

Monoclonal

Ab Purification Comment :

By protein-G affinity chromatography

Product Type Name :

Monoclonal Antibody

UniProt No. :

P18075

Internal Search Terms :

Osteogenic protein1, Osteogenic protein 1, OP-1, OP1, OP 1, Eptotermin alfa, Bone morphogenetic protein 7, BMP 7, BMP7, BMP-7, ABM0615-10ug, ABM0615-20ug, ABM0615-50ug, ABM0615-100ug, ABM0615-250ug, ABM0615-500ug, ABM0615-1mg, ABM0615-010, ABM0615-020, ABM0615-050, ABM0615-100, ABM0615-250, ABM0615-500, ABM0615-01M

more info or order :

NKMAX product webpage