Recombinant human HLA-DRB1 protein | NKGen Biotech ATGP2585 product information

product summary

company name :

NKGen Biotech

product type :

protein

product name :

Recombinant human HLA-DRB1 protein

catalog :

ATGP2585

quantity :

20 ug

price :

80 USD

more info or order :

NKGen Biotech product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human HLA-DRB1 protein

Domain :

30-227aa

Catalog number (SKU) :

ATGP2585

NCBI :

NP_002115

Description :

HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa. It is encoded by 6 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain; and exon 5 encodes the cytoplasmic tail. Recombinant human HLA-DRB1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Major histocompatibility complex class II DR beta 1, Major histocompatibility complex, class II, DR beta 1, DRB1, HLA DRB1, HLA-DR1B, HLA-DRB1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Menendez-Benito V., et al. (2007) Immunity. 26:1-3;; De Gassart A., et al. (2008) Proc. Natl. Acad. Sci. u.S.A. 105:3491-3496;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

25.2 kDa (219aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGDTRPRFLW QPKRECHFFN GTERVRFLDR YFYNQEESVR FDSDVGEFRA VTELGRPDAE YWNSQKDILE QARAAVDTYC RHNYGVVESF TVQRRVQPKV TVYPSKTQPL QHHNLLVCSV SGFYPGSIEV RWFLNGQEEK AGMVSTGLIQ NGDWTFQTLV MLETVPRSGE VYTCQVEHPS VTSPLTVEWR ARSESAQSK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P01911

Internal Search Terms :

HLA-DRB1, Major histocompatibility complex class II DR beta 1, Major histocompatibility complex, class II, DR beta 1, DRB1, HLA DRB1, HLA-DR1B, HLA-DRB1,ATGP2585-10ug,ATGP2585-20ug,ATGP2585-50ug,ATGP2585-100ug,ATGP2585-250ug,ATGP2585-500ug,ATGP2585-1mg,ATGP2585-10,ATGP2585-20,ATGP2585-50,ATGP2585-100,ATGP2585-250,ATGP2585-500,ATGP2585-1

more info or order :

NKGen Biotech product webpage