product summary
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company name :
NKGen Biotech
product type :
protein
product name :
Recombinant human TDO2 protein
catalog :
ATGP0939
quantity :
10 ug
price :
240 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human TDO2 protein
Domain :
1-406aa
Catalog number (SKU) :
ATGP0939
NCBI :
NP_005642
Description :
TDO2, also known as TDO, is a ferrous heme enzyme that catalyzes the first and rate-limiting step in the kynurenine pathway, the major pathway of tryptophan metabolism. It incorporates oxygen into the indole moiety of tryptophan. It has a broad specificity towards tryptamine and derivatives including D- and L-tryptophan, 5-hydroxytryptophan and serotonin. Recombinant human TDO2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Tryptophan 23-dioxygenase, Tryptophan 2,3-dioxygenase, TDO, TPH2, TRPO
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Murray MF., et al. (2007) Curr Drug Metab. 8(3):197-200.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
50 kDa (426aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MSGCPFLGNN FGYTFKKLPV EGSEEDKSQT GVNRASKGGL IYGNYLHLEK VLNAQELQSE TKGNKIHDEH LFIITHQAYE LWFKQILWEL DSVREIFQNG HVRDERNMLK VVSRMHRVSV ILKLLVQQFS ILETMTALDF NDFREYLSPA SGFQSLQFRL LENKIGVLQN MRVPYNRRHY RDNFKGEENE LLLKSEQEKT LLELVEAWLE RTPGLEPHGF NFWGKLEKNI TRGLEEEFIR IQAKEESEEK EEQVAEFQKQ KEVLLSLFDE KRHEHLLSKG ERRLSYRALQ GALMIYFYRE EPRFQVPFQL LTSLMDIDSL MTKWRYNHVC MVHRMLGSKA GTGGSSGYHY LRSTVSDRYK VFVDLFNLST YLIPRHWIPK MNPTIHKFLY TAEYCDSSYF SSDESD
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P48775
Internal Search Terms :
TDO2, Tryptophan 23-dioxygenase, Tryptophan 2,3-dioxygenase, TDO, TPH2, TRPO,ATGP0939-10ug,ATGP0939-20ug,ATGP0939-50ug,ATGP0939-100ug,ATGP0939-250ug,ATGP0939-500ug,ATGP0939-1mg,ATGP0939-10,ATGP0939-20,ATGP0939-50,ATGP0939-100,ATGP0939-250,ATGP0939-500,ATGP0939-1
more info or order :
company information
NKGen Biotech
440, Changnyong-daero, Yeongtong-gu, Suwon-si, Gyeonggi-do, 16504
https://www.nkmaxbio.com82-31-8017-8114
headquarters: South Korea