Mouse Period Circadian Protein Homolog 2 (PER2) ELISA Kit | MyBioSource MBS9909846 product information

product summary

company name :

MyBioSource

product type :

ELISA/assay

product name :

Mouse Period Circadian Protein Homolog 2 (PER2) ELISA Kit

catalog :

MBS9909846

quantity :

48-Strip-Wells

price :

470 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS9909846

products type :

ELISA Kit

products full name :

Mouse Period Circadian Protein Homolog 2 (PER2) ELISA Kit

products short name :

[Period Circadian Protein Homolog 2 (PER2)]

other names :

[period circadian protein homolog 2; Period circadian protein homolog 2; period circadian protein homolog 2; period circadian regulator 2; Circadian clock protein PERIOD 2]

products gene name :

[PER2]

other gene names :

[PER2; PER2; FASPS; FASPS1; KIAA0347; hPER2]

reactivity :

Mouse

sequence length :

1255

storage stability :

Store all reagents at 2-8 degree C

other info1 :

Samples: Fish Body Fluids And Tissue Homogenates. Assay Type: Quantitative Sandwich. Detection Range: 0.625ng/ml-20ng/ml. Sensitivity: 0.1ng/ml.

other info2 :

Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100]. All CV% should be compared by concentration, not compared by OD values.

products description :

Background/Introduction: This Quantitative Sandwich ELISA kit is for lab reagent/research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determine the level of PER2 (hereafter termed "analyte") in undiluted original Fish body fluids and tissue homogenates. This kit is NOT suitable for assaying non-biological sources of substances.

ncbi gi num :

12707562

ncbi acc num :

NP_073728.1

ncbi gb acc num :

NM_022817.2

uniprot acc num :

O15055

ncbi mol weight :

45,175 Da

ncbi pathways :

BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway (477138); Circadian Clock Pathway (187173); Circadian Entrainment Pathway (698773); Circadian Entrainment Pathway (699872); Circadian Rhythm Pathway (83084); Circadian Rhythm Pathway (495); Diurnally Regulated Genes With Circadian Orthologs Pathway (198813); Herpes Simplex Infection Pathway (377873); Herpes Simplex Infection Pathway (377865); Transcriptional Misregulation In Cancer Pathway (523016)

ncbi summary :

This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014]

uniprot summary :

PER2: a transcription factor belonging to the basic helix-loop-helix (bHLH) family. A member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. Behaves as a negative element in circadian transcriptional loop. Does not appear to bind DNA, suggesting indirect transcriptional inhibition. Expression oscillates with a 24 hr rhythm in the suprachiasmatic nucleus and the whole eyes. Oscillations are maintained under constant darkness and are responsive to changes of the light/dark cycles. There is a 4 hour time delay between per1 and per2 oscillations. The expression rhythms appear to originate from retina. Protein type: Nuclear receptor co-regulator; Nucleolus; Transcription factor. Chromosomal Location of Human Ortholog: 2q37.3. Cellular Component: nucleolus; nucleus; perinuclear region of cytoplasm. Molecular Function: protein binding; transcription coactivator activity. Biological Process: circadian regulation of gene expression; circadian rhythm; fatty acid metabolic process; gluconeogenesis; glycogen biosynthetic process; lactate biosynthetic process; negative regulation of circadian rhythm; negative regulation of fat cell proliferation; negative regulation of protein ubiquitination; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription regulatory region DNA binding; negative regulation of transcription, DNA-dependent; regulation of cell cycle; regulation of circadian rhythm; regulation of glutamate uptake involved in transmission of nerve impulse; regulation of insulin secretion; regulation of neurogenesis; regulation of vasoconstriction; transcription, DNA-dependent; white fat cell differentiation. Disease: Advanced Sleep Phase Syndrome, Familial, 1

size1 :

48-Strip-Wells

price1 :

470 USD

size2 :

96-Strip-Wells

price2 :

680

size3 :

5x96-Strip-Wells

price3 :

3100

size4 :

10x96-Strip-Wells

price4 :

6095

more info or order :

MyBioSource product webpage