product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Rat Peptidyl-glycine alpha-amidating monooxygenase (Pam), partial
catalog :
MBS968591
quantity :
0.5 mg (E-Coli)
price :
1085 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS968591
products type :
Recombinant Protein
products full name :
Recombinant Rat Peptidyl-glycine alpha-amidating monooxygenase (Pam), partial
products short name :
Peptidyl-glycine alpha-amidating monooxygenase (Pam), partial
products name syn :
Peptidyl-glycine alpha-amidating monooxygenase; PAM; Including the following 2 domains:; Peptidylglycine alpha-hydroxylating monooxygenase; PHM; EC=1.14.17.3; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase; EC=4.3.2.5; Peptidylamidoglycolate lyase; P
other names :
peptidyl-glycine alpha-amidating monooxygenase; Peptidyl-glycine alpha-amidating monooxygenase; peptidyl-glycine alpha-amidating monooxygenase; peptidylglycine alpha-amidating monooxygenase; Peptidylamidoglycolate lyase; PAL
products gene name :
Pam
other gene names :
Pam; Pam; PAM; PHM; PAL
uniprot entry name :
AMD_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Rattus norvegicus (Rat)
ncbi gi num :
19923674
ncbi acc num :
NP_037132.2
ncbi gb acc num :
NM_013000.2
uniprot acc num :
P14925
ncbi mol weight :
34,676 Da
ncbi summary :
catalyzes conversion of glycine-extended peptides into biologically active alpha-amidated peptides [RGD, Feb 2006]
uniprot summary :
PAM: Bifunctional enzyme that catalyzes 2 sequential steps in C-terminal alpha-amidation of peptides. The monooxygenase part produces an unstable peptidyl(2-hydroxyglycine) intermediate that is dismutated to glyoxylate and the corresponding desglycine peptide amide by the lyase part. C-terminal amidation of peptides such as neuropeptides is essential for full biological activity. 6 isoforms of the human protein are produced by alternative splicing. Protein type: EC 1.14.17.3; Vesicle; Lyase; Oxidoreductase; EC 4.3.2.5; Membrane protein, integral. Cellular Component: extracellular space; neuron projection; cell surface; cell soma; membrane; perinuclear region of cytoplasm; secretory granule membrane; integral to membrane; plasma membrane; perikaryon; trans-Golgi network; secretory granule. Molecular Function: protein binding; copper ion binding; L-ascorbic acid binding; zinc ion binding; peptidylamidoglycolate lyase activity; calcium ion binding; protein kinase binding; peptidylglycine monooxygenase activity. Biological Process: response to drug; limb development; lactation; central nervous system development; maternal process involved in pregnancy; heart development; response to glucocorticoid stimulus; long-chain fatty acid metabolic process; response to estradiol stimulus; odontogenesis; regulation of transcription from RNA polymerase II promoter; ovulation cycle process; regulation of protein secretion; peptide metabolic process; response to copper ion; peptide amidation; regulation of actin cytoskeleton organization and biogenesis; toxin metabolic process; protein metabolic process; response to hypoxia; protein amino acid amidation; protein homooligomerization; response to pH
size1 :
0.5 mg (E-Coli)
price1 :
1085 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1085
size3 :
0.5 mg (Yeast)
price3 :
1315
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1315
size5 :
1 mg (E-Coli)
price5 :
1675
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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