protein

Recombinant Mouse Talin-1 (Tln1), partial

MBS968501

0.5 mg (E-Coli)

715 USD

Recombinant Protein

Recombinant Mouse Talin-1 (Tln1), partial

Talin-1 (Tln1), partial

Talin-1

talin-1; Talin-1; talin-1; talin 1

Tln1

Tln1; Tln

Tln1; Tln1; Tln; Tln

TLN1_MOUSE

E Coli or Yeast or Baculovirus or Mammalian Cell

>90%

Liquid containing glycerol; lyophilization may be available upon request.

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Species: Mus musculus (Mouse)

Probably involved in connections of major cytoskeletal structures to the plasma membrane. High molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts.

227116327

NP_035732.2

NM_011602.5

P26039

35kD

Axon Guidance Pathway (970585); Developmental Biology Pathway (970813); Focal Adhesion Pathway (198353); Focal Adhesion Pathway (83264); Focal Adhesion Pathway (478); GRB2:SOS Provides Linkage To MAPK Signaling For Integrins Pathway (1000999); HTLV-I Infection Pathway (373903); HTLV-I Infection Pathway (373889); Hemostasis Pathway (1001295); IRE1alpha Activates Chaperones Pathway (1000426)

Talin-1: a cytoskeletal protein which is concentrated in areas of cell-substratum and cell-cell contacts. This protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Cellular Component: ruffle; focal adhesion; cell projection; cytoskeleton; membrane; cytoplasm; plasma membrane; microtubule organizing center; cell junction. Molecular Function: integrin binding; actin filament binding; protein binding; LIM domain binding; structural constituent of cytoskeleton; protein complex binding; actin binding; insulin receptor binding; vinculin binding. Biological Process: cytoskeletal anchoring; cell-substrate junction assembly; cortical actin cytoskeleton organization and biogenesis; cell adhesion

0.5 mg (E-Coli)

715 USD

0.5 mg (Yeast)

950

0.05 mg (Baculovirus)

950

1 mg (E-Coli)

1170

0.05 mg (Mammalian-Cell)

1170