catalog number :
MBS968183
products type :
Recombinant Protein
products full name :
Recombinant Macaca mulatta (Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1)
products short name :
(Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1)
products name syn :
Recombinant (Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1); Interferon-induced GTP-binding protein Mx1; Myxoma resistance protein 1 Myxovirus resistance protein 1 Cleaved into the following chain: 1. Interferon-induced GTP-binding prote
other names :
interferon-induced GTP-binding protein Mx1; Interferon-induced GTP-binding protein Mx1; interferon-induced GTP-binding protein Mx1; myxoma resistance protein 1; myxovirus resistance protein 1; Myxoma resistance protein 1; Myxovirus resistance protein 1
products gene name syn :
MX1
other gene names :
MX1; MX1
uniprot entry name :
MX1_MACMU
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-661
sequence :
VLSEVDIVKADPAAASQPLLLNGDADVAQKSPGSVAENN
LCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQ
SSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNED
EWRGKVSYQDYEIEILDASEVEKEINKAQNTIAGEGMGI
SHELITLEISSRDVPDLTLIDLPGITRVAVGNQPPDIGY
KIKTLIRKYIQRQETINLVVVPSNVDIATTEALSMAQEV
DPEGDRTIGILTKPDLVDKGTEDKVVDVVRNLVFHLKKG
YMIVKCRGQQEIQDQLSLSEALQREKIFFEDHPHFRDLL
EEGKATIPCLAEKLTSELIAHICKSLPLLENQIKESHQG
ITEELQKYGVDIPEDENEKMFFLIDKINAFNQDITALIQ
GEETVGEDDSRLFTRLRREFHKWGIIIENNLQEGHKITS
RKMQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPA
VNMLHTVTDMVRLAFTDVSMKNFEELFNLHRTAKSKIED
IRTEQEREGEKLIRLHFQMEQIVYCQDQVYRGALQKVRE
KELEEEKKKKSWDIGTFQPSSTESSMEEIFQHLMAYHQE
ASKRISSHIPLVIQFFMLQMYGQQLQKAMLQLLQDKDTY
SWLLKERSDTSDKRKFLKERLARLTQARRRLAQFPG
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Macaca mulatta (Rhesus macaque)
ncbi acc num :
NP_001073161.1
ncbi gb acc num :
NM_001079693.2
ncbi mol weight :
75,431 Da
ncbi pathways :
Influenza A Pathway (217176); Influenza A Pathway (217150); Measles Pathway (213310); Measles Pathway (213277)
uniprot summary :
Function: Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens . By similarity.May regulate the calcium channel activity of TRPCs. Ring-like assemblies may induce membrane tubulation . By similarity. Subunit structure: Oligomerizes (via the stalk domain) in a criss-cross pattern to form a linear stalk filament, may form ring-like structures with a 24 Angstrom inner diameter. Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7 . By similarity. Subcellular location: Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side . By similarity. Note: Binds preferentially to negatively charged phospholipids . By similarity. Induction: By type I and type III interferons. Sequence similarities: Belongs to the dynamin family.Contains 1 GED domain.