protein

Recombinant Human Glutamate receptor 1 (GRIA1)

MBS968151

1 mg (E-Coli)

1170 USD

Recombinant Protein

Recombinant Human Glutamate receptor 1 (GRIA1)

Glutamate receptor 1 (GRIA1)

Recombinant Glutamate receptor 1 (GRIA1); Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1 GluR-A GluR-K1 Glutamate receptor ionotropic, AMPA 1; GluA1

glutamate receptor 1 isoform 1; Glutamate receptor 1; glutamate receptor 1; AMPA 1; gluR-1; gluR-A; gluR-K1; AMPA-selective glutamate receptor 1; glutamate receptor, ionotropic, AMPA 1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic, AMPA 1

GRIA1; GLUH1, GLUR1

GRIA1; GRIA1; GLUH1; GLUR1; GLURA; GluA1; HBGR1; GLUH1; GLUR1; GluR-1; GluA1

GRIA1_HUMAN

E Coli or Yeast or Baculovirus or Mammalian Cell

201-300

>90%

Liquid containing glycerol; lyophilization may be available upon request.

Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

Species: Homo sapiens (Human)

167001419

NP_000818.2

NM_000827.3

P42261

101,506 Da

Activation Of AMPA Receptors Pathway (106539); Activation Of NMDA Receptor Upon Glutamate Binding And Postsynaptic Events Pathway (161033); Amphetamine Addiction Pathway (547607); Amphetamine Addiction Pathway (550546); Amyotrophic Lateral Sclerosis (ALS) Pathway (83099); Amyotrophic Lateral Sclerosis (ALS) Pathway (511); Dopaminergic Synapse Pathway (469199); Dopaminergic Synapse Pathway (469185); EPHB Forward Signaling Pathway (138047); Glutamate Binding, Activation Of AMPA Receptors And Synaptic Plasticity Pathway (106536)

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GluR1: an integral membrane protein belonging to the glutamate-gated ion channel family. L-glutamate (Glu) acts as an excitatory neurotransmitter at many synapses in the central nervous system. Glutamate receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Each of the four GluR proteins (GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. Expressed in granule and pyramidal cells in the hippocampal formation. Protein type: Channel, calcium; Channel, ligand-gated; Membrane protein, multi-pass; Membrane protein, integral. Chromosomal Location of Human Ortholog: 5q31.1. Cellular Component: postsynaptic membrane; recycling endosome; endoplasmic reticulum membrane; synaptic vesicle; cell surface; cell soma; postsynaptic density; dendrite; dendritic spine; plasma membrane; cell junction. Molecular Function: protein binding; extracellular-glutamate-gated ion channel activity; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity; glutamate receptor activity; PDZ domain binding. Biological Process: synaptic transmission; synaptic transmission, glutamatergic; long-term memory; ionotropic glutamate receptor signaling pathway; receptor internalization; signal transduction

1 mg (E-Coli)

1170 USD

1 mg (Yeast)

1835