product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Keratin, type II cuticular Hb5 (KRT85)
catalog :
MBS967781
quantity :
0.5 mg (E-Coli)
price :
1295 USD
more info or order :
product information
catalog number :
MBS967781
products type :
Recombinant Protein
products full name :
Recombinant Human Keratin, type II cuticular Hb5 (KRT85)
products short name :
Keratin, type II cuticular Hb5 (KRT85)
products name syn :
Keratin, type II cuticular Hb5; Hair keratin K2.12; Keratin-85; K85; Type II hair keratin Hb5; Type-II keratin Kb25
other names :
keratin, type II cuticular Hb5 isoform 1; Keratin, type II cuticular Hb5; keratin, type II cuticular Hb5; keratin-85; hair keratin K2.12; type-II keratin Kb25; keratin, hair, basic, 5; hard keratin, type II, 5; type II hair keratin Hb5; keratin 85; Hair keratin K2.12; Keratin-85; K85; Type II hair keratin Hb5; Type-II keratin Kb25
products gene name :
KRT85
products gene name syn :
KRT85; KRTHB5
other gene names :
KRT85; KRT85; HB5; K85; Hb-5; hHb5; ECTD4; KRTHB5; KRTHB5; K85
uniprot entry name :
KRT85_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-507
sequence length :
507
sequence :
MSCRSYRISS GCGVTRNFSS CSAVAPKTGN RCCISAAPYR GVSCYRGLTG FGSRSLCNLG SCGPRIAVGG FRAGSCGRSF GYRSGGVCGP SPPCITTVSV NESLLTPLNL EIDPNAQCVK QEEKEQIKSL NSRFAAFIDK VRFLEQQNKL LETKWQFYQN QRCCESNLEP LFSGYIETLR REAECVEADS GRLASELNHV QEVLEGYKKK YEEEVALRAT AENEFVVLKK DVDCAYLRKS DLEANVEALV EESSFLRRLY EEEIRVLQAH ISDTSVIVKM DNSRDLNMDC IIAEIKAQYD DVASRSRAEA ESWYRSKCEE MKATVIRHGE TLRRTKEEIN ELNRMIQRLT AEIENAKCQR AKLEAAVAEA EQQGEAALSD ARCKLAELEG ALQKAKQDMA CLLKEYQEVM NSKLGLDIEI ATYRRLLEGE EHRLCEGVGS VNVCVSSSRG GVSCGGLSYS TTPGRQITSG PSAIGGSITV VAPDSCAPCQ PRSSSFSCGS SRSVRFA
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi gi num :
4504935
ncbi acc num :
NP_002274.1
ncbi gb acc num :
NM_002283.3
uniprot acc num :
P78386
ncbi mol weight :
60kD
ncbi summary :
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. [provided by RefSeq, Jul 2008]
uniprot summary :
K85: Defects in KRT85 are the cause of ectodermal dysplasia pure hair-nail type (EDPHN). Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EDPHN is characterized by complete alopecia, hypotricosis and nail dystrophy in all digits. There is no evidence of any other abnormality. Inheritance can be autosomal dominant or recessive. Belongs to the intermediate filament family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 12q13. Cellular Component: extracellular space; keratin filament. Molecular Function: structural molecule activity. Biological Process: epidermis development. Disease: Ectodermal Dysplasia 4, Hair/nail Type
size1 :
0.5 mg (E-Coli)
price1 :
1295 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1295
size3 :
0.5 mg (Yeast)
price3 :
1515
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1515
size5 :
1 mg (E-Coli)
price5 :
2130
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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