product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Alanine aminotransferase 1
catalog :
MBS967131
quantity :
0.05 mg (E-Coli)
price :
190 USD
more info or order :
product information
catalog number :
MBS967131
products type :
Recombinant Protein
products full name :
Recombinant Human Alanine aminotransferase 1
products short name :
Alanine aminotransferase 1
products name syn :
Glutamate pyruvate transaminase 1; GPT 1; Glutamic-alanine transaminase 1; Glutamic-pyruvic transaminase 1
other names :
alanine aminotransferase 1; Alanine aminotransferase 1; alanine aminotransferase 1; glutamic-pyruvate transaminase (alanine aminotransferase); Glutamate pyruvate transaminase 1; GPT 1; Glutamic--alanine transaminase 1; Glutamic--pyruvic transaminase 1
products gene name :
GPT
other gene names :
GPT; GPT; AAT1; ALT1; GPT1; AAT1; GPT1; ALT1; GPT 1
uniprot entry name :
ALAT1_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-496
sequence length :
496
sequence :
ASSTGDRSQAVRHGLRAKVLTLDGMNPRVRRVEYAVRGP
IVQRALELEQELRQGVKKPFTEVIRANIGDAQAMGQRPI
TFLRQVLALCVNPDLLSSPNFPDDAKKRAERILQACGGH
SLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLS
TGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATL
AELGAVQVDYYLDEERAWALDVAELHRALGQARDHCRPR
ALCVINPGNPTGQVQTRECIE
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products categories :
Signal Transduction
products description :
Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles.
products references :
Human glutamate pyruvate transaminase (GPT)
ncbi gi num :
4885351
ncbi acc num :
NP_005300.1
ncbi gb acc num :
NM_005309.2
uniprot acc num :
P24298
ncbi mol weight :
58.6kD
ncbi pathways :
2-Oxocarboxylic Acid Metabolism Pathway (714485); 2-Oxocarboxylic Acid Metabolism Pathway (717400); Alanine And Aspartate Metabolism Pathway (198783); Alanine, Aspartate And Glutamate Metabolism Pathway (101142); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Amino Acid Synthesis And Interconversion (transamination) Pathway (1270159); Arginine Biosynthesis Pathway (82943); Arginine Biosynthesis Pathway (306); Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174)
ncbi summary :
This gene encodes cytosolic alanine aminotransaminase 1 (ALT1); also known as glutamate-pyruvate transaminase 1. This enzyme catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate and, therefore, plays a key role in the intermediary metabolism of glucose and amino acids. Serum activity levels of this enzyme are routinely used as a biomarker of liver injury caused by drug toxicity, infection, alcohol, and steatosis. A related gene on chromosome 16 encodes a putative mitochondrial alanine aminotransaminase.[provided by RefSeq, Nov 2009]
uniprot summary :
GPT: Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles. Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily. Protein type: EC 2.6.1.2; Transferase; Amino Acid Metabolism - alanine, aspartate and glutamate. Chromosomal Location of Human Ortholog: 8q24.3. Cellular Component: cytosol. Molecular Function: alanine transaminase activity; pyridoxal phosphate binding. Biological Process: amino acid biosynthetic process; L-alanine catabolic process
size1 :
0.05 mg (E-Coli)
price1 :
190 USD
size2 :
0.05 mg (Yeast)
price2 :
190
size3 :
0.2 mg (E-Coli)
price3 :
460
size4 :
0.2 mg (Yeast)
price4 :
460
size5 :
0.5 mg (Yeast)
price5 :
750
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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