catalog number :
MBS967079
products type :
Recombinant Protein
products full name :
Recombinant Human Histidine decarboxylase (HDC)
products short name :
Histidine decarboxylase (HDC)
products name syn :
Histidine decarboxylase; HDC; EC=4.1.1.22
other names :
histidine decarboxylase; Histidine decarboxylase; histidine decarboxylase; histidine decarboxylase
other gene names :
HDC; HDC; HDC
uniprot entry name :
DCHS_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-662
sequence :
MMEPEEYRER GREMVDYICQ YLSTVRERRV TPDVQPGYLR AQLPESAPED PDSWDSIFGD IERIIMPGVV HWQSPHMHAY YPALTSWPSL LGDMLADAIN CLGFTWASSP ACTELEMNVM DWLAKMLGLP EHFLHHHPSS QGGGVLQSTV SESTLIALLA ARKNKILEMK TSEPDADESC LNARLVAYAS DQAHSSVEKA GLISLVKMKF LPVDDNFSLR GEALQKAIEE DKQRGLVPVF VCATLGTTGV CAFDCLSELG PICAREGLWL HIDAAYAGTA FLCPEFRGFL KGIEYADSFT FNPSKWMMVH FDCTGFWVKD KYKLQQTFSV NPIYLRHANS GVATDFMHWQ IPLSRRFRSV KLWFVIRSFG VKNLQAHVRH GTEMAKYFES LVRNDPSFEI PAKRHLGLVV FRLKGPNCLT ENVLKEIAKA GRLFLIPATI QDKLIIRFTV TSQFTTRDDI LRDWNLIRDA ATLILSQHCT SQPSPRVGNL ISQIRGARAW ACGTSLQSVS GAGDDPVQAR KIIKQPQRVG AGPMKRENGL HLETLLDPVD DCFSEEAPDA TKHKLSSFLF SYLSVQTKKK TVRSLSCNSV PVSAQKPLPT EASVKNGGSS RVRIFSRFPE DMMMLKKSAF KKLIKFYSVP SFPECSSQCG LQLPCCPLQA MV
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi acc num :
NP_002103.2
ncbi gb acc num :
NM_002112.3
ncbi pathways :
Biogenic Amine Synthesis Pathway (198793); Histidine Catabolism Pathway (106186); Histidine Metabolism Pathway (82958); Histidine Metabolism Pathway (324); Metabolism Pathway (477135); Metabolism Of Amino Acids And Derivatives Pathway (106169); Histamine Biosynthesis Pathway (545324)
ncbi summary :
This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]
uniprot summary :
HDC: a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.[provided by RefSeq, Aug 2010]. Protein type: Lyase; Amino Acid Metabolism - histidine; EC 4.1.1.22. Chromosomal Location of Human Ortholog: 15q21.2. Cellular Component: cytosol. Molecular Function: pyridoxal phosphate binding; histidine decarboxylase activity. Biological Process: catecholamine biosynthetic process; histamine biosynthetic process; histidine metabolic process; histidine catabolic process. Disease: Gilles De La Tourette Syndrome
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)