catalog number :
MBS966816
products type :
Recombinant Protein
products full name :
Recombinant Macaca mulatta (Rhesus macaque) fMet-Leu-Phe receptor (FPR1)
products short name :
(Rhesus macaque) fMet-Leu-Phe receptor (FPR1)
products name syn :
Recombinant (Rhesus macaque) fMet-Leu-Phe receptor (FPR1); fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR N-formylpeptide chemoattractant receptor
other names :
fMet-Leu-Phe receptor; fMet-Leu-Phe receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
products gene name syn :
FPR1
other gene names :
FPR1; fMLP receptor; FPR
uniprot entry name :
FPR1_MACMU
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-346
sequence :
NSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVL
GNGLVIWVAGFRMRHTVTTISYLNLAVADFCFTSTLPFL
MVVKVMRGHWPFGWFLCKFIFTIVDINLFGSVFLIALIA
LDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLP
VIIRVTTVPGKTGTVACTFDFSPWTNDPVEKLKVTIAML
TVRGIIRFIIGFSVPMSIVAVSYGLIATKIHKQGLIKSS
RPLRVLSFVVAAFFLCWSPYQVVAFIATVRLRNILQGLS
KELRIAVDATSALAFFNSCLNPMLYVFMGQDFRERLIHS
LPTSLERALTEDSAQTSDTATNSTLPSAEVPLQA
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Macaca mulatta (Rhesus macaque)
ncbi mol weight :
38,099 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
uniprot summary :
Function: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Subcellular location: Cell membrane; Multi-pass membrane protein. Post-translational modification: Phosphorylated; which is necessary for desensitization . By similarity. Sequence similarities: Belongs to the G-protein coupled receptor 1 family.