catalog number :
MBS966114
products type :
Recombinant Protein
products full name :
Recombinant Human Achaete-scute homolog 1 (ASCL1)
products short name :
Achaete-scute homolog 1 (ASCL1)
other names :
achaete-scute homolog 1; Achaete-scute homolog 1; achaete-scute homolog 1; ASH-1; achaete scute protein; achaete-scute complex-like 1; achaete-scute complex homolog 1; class A basic helix-loop-helix protein 46; achaete-scute family bHLH transcription factor 1; Class A basic helix-loop-helix protein 46; bHLHa46
products gene name :
ASCL1
other gene names :
ASCL1; ASCL1; ASH1; HASH1; MASH1; bHLHa46; ASH1; BHLHA46; HASH1; ASH-1; hASH1; bHLHa46
uniprot entry name :
ASCL1_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-236
sequence :
MESSAKMESG GAGQQPQPQP QQPFLPPAAC FFATAAAAAA AAAAAAAQSA QQQQQQQQQQ QQAPQLRPAA DGQPSGGGHK SAPKQVKRQR SSSPELMRCK RRLNFSGFGY SLPQQQPAAV ARRNERERNR VKLVNLGFAT LREHVPNGAA NKKMSKVETL RSAVEYIRAL QQLLDEHDAV SAAFQAGVLS PTISPNYSND LNSMAGSPVS SYSSDEGSYD PLSPEEQELL DFTNWF
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi acc num :
NP_004307.2
ncbi gb acc num :
NM_004316.3
ncbi mol weight :
25,454 Da
ncbi pathways :
Delta-Notch Signaling Pathway 198879!!Notch-mediated HES/HEY Network Pathway 169347!!SIDS Susceptibility Pathways 198901
ncbi summary :
This gene encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. The protein activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. This protein plays a role in the neuronal commitment and differentiation and in the generation of olfactory and autonomic neurons. Mutations in this gene may contribute to the congenital central hypoventilation syndrome (CCHS) phenotype in rare cases. [provided by RefSeq, Jul 2008]
size :
1 mg (E Coli Derived)