catalog number :
MBS965807
products type :
Recombinant Protein
products full name :
Recombinant Human Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT1)
products short name :
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (MGAT1)
other names :
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; glcNAc-T I; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase I; GNT-I; GlcNAc-T I
products gene name :
MGAT1
other gene names :
MGAT1; MGAT1; MGAT; GLCT1; GLYT1; GNT-1; GNT-I; GLCNAC-TI; GGNT1; GLCT1; GLYT1; MGAT; GNT-I; GlcNAc-T I
uniprot entry name :
MGAT1_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-445
sequence :
MLKKQSAGLV LWGAILFVAW NALLLLFFWT RPAPGRPPSV SALDGDPASL TREVIRLAQD AEVELERQRG LLQQIGDALS SQRGRVPTAA PPAQPRVPVT PAPAVIPILV IACDRSTVRR CLDKLLHYRP SAELFPIIVS QDCGHEETAQ AIASYGSAVT HIRQPDLSSI AVPPDHRKFQ GYYKIARHYR WALGQVFRQF RFPAAVVVED DLEVAPDFFE YFRATYPLLK ADPSLWCVSA WNDNGKEQMV DASRPELLYR TDFFPGLGWL LLAELWAELE PKWPKAFWDD WMRRPEQRQG RACIRPEISR TMTFGRKGVS HGQFFDQHLK FIKLNQQFVH FTQLDLSYLQ REAYDRDFLA RVYGAPQLQV EKVRTNDRKE LGEVRVQYTG RDSFKAFAKA LGVMDDLKSG VPRAGYRGIV TFQFRGRRVH LAPPLTWEGY DPSWN
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi acc num :
NP_001108089.1
ncbi gb acc num :
NM_001114617.1
ncbi mol weight :
50,878 Da
ncbi pathways :
Asparagine N-linked Glycosylation Pathway 161013!!Metabolism Of Proteins Pathway 106230!!N-Glycan Biosynthesis Pathway 82975!!N-Glycan Biosynthesis Pathway 345!!N-glycan Trimming And Elongation In The Cis-Golgi Pathway 187221!!Post-translational Protein Modification Pathway 161012!!Signal Transduction Pathway 477114!!Signaling By Wnt Pathway 106510!!Transport To The Golgi And Subsequent Modification Pathway 187220!!WNT Ligand Biogenesis And Trafficking Pathway 833832
ncbi summary :
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
size :
1 mg (E Coli Derived)