Recombinant Human POU domain, class 3, transcription factor 2 (POU3F2) | MyBioSource MBS965406 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human POU domain, class 3, transcription factor 2 (POU3F2)

catalog :

MBS965406

quantity :

0.5 mg (E-Coli)

price :

1220 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS965406

products type :

Recombinant Protein

products full name :

Recombinant Human POU domain, class 3, transcription factor 2 (POU3F2)

products short name :

POU domain, class 3, transcription factor 2 (POU3F2)

products name syn :

POU domain, class 3, transcription factor 2; Brain-specific homeobox/POU domain protein 2; Brain-2; Brn-2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Octamer-binding protein 7; Oct-7; Octamer-binding transcription factor 7; OTF-

other names :

POU domain, class 3, transcription factor 2; POU domain, class 3, transcription factor 2; POU domain, class 3, transcription factor 2; brain-2; octamer-binding protein 7; octamer-binding transcription factor 7; brain-specific homeobox/POU domain protein 2; nervous system-specific octamer-binding transcription factor N-Oct-3; POU class 3 homeobox 2; Brain-specific homeobox/POU domain protein 2; Brain-2; Brn-2; Nervous system-specific octamer-binding transcription factor N-Oct-3; Octamer-binding protein 7; Oct-7; Octamer-binding transcription factor 7; OTF-7

products gene name :

POU3F2

products gene name syn :

POU3F2; BRN2; OCT7; OTF7

other gene names :

POU3F2; POU3F2; BRN2; OCT7; OTF7; OTF-7; POUF3; brn-2; oct-7; N-Oct3; BRN2; OCT7; OTF7; Brain-2; Brn-2; Oct-7; OTF-7

uniprot entry name :

PO3F2_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

1-443

sequence length :

443

sequence :

MATAASNHYS LLTSSASIVH AEPPGGMQQG AGGYREAQSL VQGDYGALQS NGHPLSHAHQ WITALSHGGG GGGGGGGGGG GGGGGGGGDG SPWSTSPLGQ PDIKPSVVVQ QGGRGDELHG PGALQQQHQQ QQQQQQQQQQ QQQQQQQQQR PPHLVHHAAN HHPGPGAWRS AAAAAHLPPS MGASNGGLLY SQPSFTVNGM LGAGGQPAGL HHHGLRDAHD EPHHADHHPH PHSHPHQQPP PPPPPQGPPG HPGAHHDPHS DEDTPTSDDL EQFAKQFKQR RIKLGFTQAD VGLALGTLYG NVFSQTTICR FEALQLSFKN MCKLKPLLNK WLEEADSSSG SPTSIDKIAA QGRKRKKRTS IEVSVKGALE SHFLKCPKPS AQEITSLADS LQLEKEVVRV WFCNRRQKEK RMTPPGGTLP GAEDVYGGSR DTPPHHGVQT PVQ

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

products description :

Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ('GCAT') and ('TAAT'), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters (By similarity).

ncbi gi num :

51702521

ncbi acc num :

NP_005595.2

ncbi gb acc num :

NM_005604.3

uniprot acc num :

P20265

ncbi mol weight :

49kD

ncbi pathways :

SIDS Susceptibility Pathways (198901)

ncbi summary :

This gene encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. Overexpression of this protein is associated with an increase in the proliferation of melanoma cells. [provided by RefSeq, Mar 2012]

uniprot summary :

Oct7: Transcription factor that binds preferentially to the recognition sequence which consists of two distinct half-sites, ( GCAT ) and ( TAAT ), separated by a nonconserved spacer region of 0, 2, or 3 nucleotides. Positively regulates the genes under the control of corticotropin-releasing hormone (CRH) and CRH II promoters. Interacts with PQBP1. Expressed specifically in the neuroectodermal cell lineage. Belongs to the POU transcription factor family. Class- 3 subfamily. 3 isoforms of the human protein are produced by alternative initiation. Protein type: DNA-binding; Motility/polarity/chemotaxis; Transcription factor. Chromosomal Location of Human Ortholog: 6q16. Cellular Component: transcription factor complex; nucleus. Molecular Function: identical protein binding; protein binding; sequence-specific DNA binding; transcription factor activity. Biological Process: neuron differentiation; epidermis development; neurohypophysis development; transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; cerebral cortex radially oriented cell migration; hypothalamus cell differentiation; positive regulation of multicellular organism growth; regulation of axonogenesis; astrocyte development; forebrain ventricular zone progenitor cell division; myelination in the peripheral nervous system

size1 :

0.5 mg (E-Coli)

price1 :

1220 USD

size2 :

0.05 mg (Baculovirus)

price2 :

1220

size3 :

0.5 mg (Yeast)

price3 :

1440

size4 :

0.05 mg (Mammalian-Cell)

price4 :

1440

size5 :

1 mg (E-Coli)

price5 :

1980

more info or order :

MyBioSource product webpage