product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Tubulin beta-4A chain (TUBB4A)
catalog :
MBS964614
quantity :
0.01 mg (Yeast)
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS964614
products type :
Recombinant Protein
products full name :
Recombinant Human Tubulin beta-4A chain (TUBB4A)
products short name :
Tubulin beta-4A chain
products name syn :
Tubulin 5 beta; Tubulin beta-4 chain
other names :
tubulin beta-4A chain isoform 1; Tubulin beta-4A chain; tubulin beta-4A chain; tubulin beta 4A class IVa; Tubulin 5 beta; Tubulin beta-4 chain
products gene name :
TUBB4A
other gene names :
TUBB4A; TUBB4A; DYT4; TUBB4; beta-5; TUBB4; TUBB5
uniprot entry name :
TBB4A_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-444
sequence length :
495
sequence :
MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGD
SDLQLERINVYYNEATGGNYVPRAVLVDLEPGTMDSVRS
GPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVL
DVVRKEAESCDCLQGFQLTHSLGGGTGSGMGTLLISKIR
EEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVEN
TDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMS
GVTTCLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPL
TSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLT
VAAVFRGRMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKT
AVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR
RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDAT
AEEGEFEEEAEEEVA
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info2 :
Species: Homo sapiens (Human)
products categories :
Signal Transduction
products description :
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
products references :
Sequence of an expressed human beta-tubulin gene containing ten Alu family members." Lee M.G.-S., Loomis C., Cowan N.J. Nucleic Acids Res. 12:5823-5836(1984)
ncbi gi num :
574584803
ncbi acc num :
NP_001276052.1
ncbi gb acc num :
NM_001289123.1
uniprot acc num :
P04350
ncbi mol weight :
53.65kD
ncbi pathways :
Anchoring Of The Basal Body To The Plasma Membrane Pathway (1268847); Assembly Of The Primary Cilium Pathway (1268846); Cell Cycle Pathway (1269741); Cell Cycle, Mitotic Pathway (1269763); Centrosome Maturation Pathway (1269805); Chaperonin-mediated Protein Folding Pathway (1268694); Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway (1268695); Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway (1268697); G2/M Transition Pathway (1269799); Gap Junction Pathway (83072)
ncbi summary :
This gene encodes a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene cause hypomyelinating leukodystrophy-6 and autosomal dominant torsion dystonia-4. Alternate splicing results in multiple transcript variants encoding different isoforms. A pseudogene of this gene is found on chromosome X. [provided by RefSeq, Jan 2014]
uniprot summary :
TUBB4: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. Belongs to the tubulin family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: cell soma; cilium; cytosol; internode region of axon; microtubule; myelin sheath; nucleus. Molecular Function: GTP binding; GTPase activity; protein binding; structural constituent of cytoskeleton. Biological Process: 'de novo' posttranslational protein folding; cellular protein metabolic process; G2/M transition of mitotic cell cycle; microtubule-based process; mitotic cell cycle; organelle organization and biogenesis; protein folding. Disease: Dystonia 4, Torsion, Autosomal Dominant
size1 :
0.01 mg (Yeast)
price1 :
140 USD
size2 :
0.05 mg (Yeast)
price2 :
245
size3 :
0.2 mg (Yeast)
price3 :
605
size4 :
0.5 mg (Yeast)
price4 :
990
size5 :
1 mg (Yeast)
price5 :
1550
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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