catalog number :
MBS964585
products type :
Recombinant Protein
products full name :
Recombinant Human Nuclear receptor ROR-alpha (RORA)
products short name :
Nuclear receptor ROR-alpha (RORA)
other names :
nuclear receptor ROR-alpha isoform c; Nuclear receptor ROR-alpha; nuclear receptor ROR-alpha; nuclear receptor RZR-alpha; transcription factor RZR-alpha; retinoid-related orphan receptor alpha; nuclear receptor subfamily 1 group F member 1; thyroid hormone nuclear receptor alpha variant 4; retinoic acid receptor-related orphan receptor alpha; RAR-related orphan receptor A; Nuclear receptor RZR-alpha; Nuclear receptor subfamily 1 group F member 1; RAR-related orphan receptor A; Retinoid-related orphan receptor-alpha
products gene name :
RORA
other gene names :
RORA; RORA; ROR1; ROR2; ROR3; RZRA; NR1F1; RZR-ALPHA; NR1F1; RZRA
uniprot entry name :
RORA_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-556
sequence :
MNEGAPGDSD LETEARVPWS IMGHCLRTGQ ARMSATPTPA GEGARRDELF GILQILHQCI LSSGDAFVLT GVCCSWRQNG KPPYSQKEDK EVQTGYMNAQ IEIIPCKICG DKSSGIHYGV ITCEGCKGFF RRSQQSNATY SCPRQKNCLI DRTSRNRCQH CRLQKCLAVG MSRDAVKFGR MSKKQRDSLY AEVQKHRMQQ QQRDHQQQPG EAEPLTPTYN ISANGLTELH DDLSNYIDGH TPEGSKADSA VSSFYLDIQP SPDQSGLDIN GIKPEPICDY TPASGFFPYC SFTNGETSPT VSMAELEHLA QNISKSHLET CQYLREELQQ ITWQTFLQEE IENYQNKQRE VMWQLCAIKI TEAIQYVVEF AKRIDGFMEL CQNDQIVLLK AGSLEVVFIR MCRAFDSQNN TVYFDGKYAS PDVFKSLGCE DFISFVFEFG KSLCSMHLTE DEIALFSAFV LMSADRSWLQ EKVKIEKLQQ KIQLALQHVL QKNHREDGIL TKLICKVSTL RALCGRHTEK LMAFKAIYPD IVRLHFPPLY KELFTSEFEP AMQIDG
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi acc num :
NP_002934.1
ncbi gb acc num :
NM_002943.3
ncbi mol weight :
53,556 Da
ncbi pathways :
Adipogenesis Pathway 198832!!BMAL1:CLOCK/NPAS2 Activates Circadian Expression Pathway 477138!!Circadian Clock Pathway 187173!!Circadian Repression Of Expression By REV-ERBA Pathway 576259!!Circadian Rhythm Pathway 83084!!Circadian Rhythm Pathway 495!!Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway 160977!!Gene Expression Pathway 105937!!Generic Transcription Pathway 105938!!Metabolism Pathway 477135
ncbi summary :
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2014]
size :
1 mg (E Coli Derived)