catalog number :
MBS963651
products type :
Recombinant Protein
products full name :
Recombinant Rat Regenerating islet-derived protein 3-gamma
products short name :
Regenerating islet-derived protein 3-gamma
products name syn :
Pancreatitis-associated protein 3; Regenerating islet-derived protein III-gamma; Reg III-gamma
other names :
regenerating islet-derived protein 3-gamma; Regenerating islet-derived protein 3-gamma; regenerating islet-derived protein 3-gamma; regenerating family member 3 gamma; Pancreatitis-associated protein 3; Regenerating islet-derived protein III-gamma; Reg III-gamma
products gene name :
Reg3g
other gene names :
Reg3g; Reg3g; Pap3; PAPIII; Pap3; REG-3-gamma; Reg III-gamma
uniprot entry name :
REG3G_RAT
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
27-174
sequence :
EDAKEDVPTSRISCPKGSRAYGSYCYALFSVSKSWFDAD
LACQKRPSGHLVSVLSGSEASFVSSLIKSSGNSGQNVWI
GLHDPTLGQEPNRGGWEWSNADVMNYFNWETNPSSVSGS
HCGTLTRASGFLRWRENNCISELPYVCKFKA
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L. monocytogenes and methicillin-resistant S. aureus. Regulates keratinocyte proliferation and differentiation after skin injury.
products references :
The pancreatitis associated protein III (PAP III)
, a new member of the PAP gene family.Frigerio J.-M., Dusetti N.J., Garrido P., Dagorn J.-C., Iovanna J.L.Biochim. Biophys. Acta 1216:329-331(1993)
Cloning, expression and chromosomal localization of the rat pancreatitis-associated protein III gene.Dusetti N.J., Frigerio J.-M., Szpirer C., Dagorn J.-C., Iovanna J.L.Biochem. J. 307:9-16(1995)
Reg3G gene expression in regenerating skeletal muscle and corresponding nerve.Klasan G.S., Ivanac D., Erzen D.J., Picard A., Takasawa S., Peharec S., Arbanas J., Girotto D., Jerkovic R.Muscle Nerve 49:61-68(2014)
ncbi acc num :
NP_775120.1
ncbi gb acc num :
NM_173097.1
ncbi mol weight :
20.34kD