product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a)
catalog :
MBS963288
quantity :
0.5 mg (E-Coli)
price :
1455 USD
more info or order :
product information
catalog number :
MBS963288
products type :
Recombinant Protein
products full name :
Recombinant Mouse Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a)
products short name :
Protein phosphatase 1 regulatory subunit 15A (Ppp1r15a)
products name syn :
Protein phosphatase 1 regulatory subunit 15A; Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116
other names :
protein phosphatase 1 regulatory subunit 15A; Protein phosphatase 1 regulatory subunit 15A; protein phosphatase 1 regulatory subunit 15A; growth arrest and DNA-damage-inducible 34; myeloid differentiation primary response gene 116; growth arrest and DNA damage-inducible protein GADD34; myeloid differentiation primary response protein MyD116; protein phosphatase 1, regulatory (inhibitor) subunit 15A; Growth arrest and DNA damage-inducible protein GADD34; Myeloid differentiation primary response protein MyD116
products gene name :
Ppp1r15a
products gene name syn :
Ppp1r15a; Gadd34; Myd116
other gene names :
Ppp1r15a; Ppp1r15a; Gadd34; Myd116; 9630030H21; Gadd34; Myd116
uniprot entry name :
PR15A_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-657
sequence length :
657
sequence :
MAPSPRPQHV LHWRDAHNFY LLSPLMGLLS RAWSRLRGPE VPEAWLAKTV TGADQIEAAA LLTPTPVSGN LLPHGETEES GSPEQSQAAQ RLCLVEAESS PPETWGLSNV DEYNAKPGQD DLREKEMERT AGKATLQPAG LQGADKRLGE VVAREEGVAE PAYPTSQLEG GPAENEEDGE TVKTYQASAA SIAPGYKPST PVPFLGEAEH QATEEKGTEN KADPSNSPSS GSHSRAWEYY SREKPKQEGE AKVEAHRAGQ GHPCRNAEAE EGGPETTFVC TGNAFLKAWV YRPGEDTEEE DNSDSDSAEE DTAQTGATPH TSAFLKAWVY RPGEDTEEED SDSDSAEEDT AQTGATPHTS AFLKAWVYRP GEDTEEENSD LDSAEEDTAQ TGATPHTSAF LKAWVYRPGE DTEEENSDLD SAEEDTAQTG ATPHTSPFLK AWVYRPGEDT EDDTEEEEDS ENVAPGDSET ADSSQSPCLQ PQRCLPGEKT KGRGEEPPLF QVAFYLPGEK PESPWAAPKL PLRLQRRLRL FKAPTRDQDP EIPLKARKVH FAEKVTVHFL AVWAGPAQAA RRGPWEQFAR DRSRFARRIA QAEEKLGPYL TPDSRARAWA RLRNPSLPQS EPRSSSEATP LTQDVTTPSP LPSETPSPSL YLGGRRG
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
ncbi gi num :
6678978
ncbi acc num :
NP_032680.1
ncbi gb acc num :
NM_008654.2
uniprot acc num :
P17564
ncbi mol weight :
63,474 Da
ncbi pathways :
Downregulation Of TGF-beta Receptor Signaling Pathway (819823); Protein Processing In Endoplasmic Reticulum Pathway (167331); Protein Processing In Endoplasmic Reticulum Pathway (167190); Signal Transduction Pathway (819739); Signaling By TGF-beta Receptor Complex Pathway (819821); TGF-beta Receptor Signaling Activates SMADs Pathway (819822)
uniprot summary :
GADD34: Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on Ser-15 . Belongs to the PPP1R15 family. Protein type: DNA repair, damage; Cell cycle regulation; Apoptosis; Translation initiation. Cellular Component: Golgi apparatus; mitochondrial outer membrane; mitochondrion; membrane; endoplasmic reticulum; cytoplasm; protein phosphatase type 1 complex. Molecular Function: protein phosphatase regulator activity; protein kinase binding; protein phosphatase binding; protein phosphatase 1 binding. Biological Process: regulation of translation; positive regulation of phosphoprotein phosphatase activity; negative regulation of protein amino acid dephosphorylation; unfolded protein response; apoptosis; negative regulation of phosphoprotein phosphatase activity; positive regulation of peptidyl-serine phosphorylation; positive regulation of transcription from RNA polymerase I promoter
size1 :
0.5 mg (E-Coli)
price1 :
1455 USD
size2 :
0.05 mg (Baculovirus)
price2 :
1455
size3 :
0.5 mg (Yeast)
price3 :
1685
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1685
size5 :
1 mg (E-Coli)
price5 :
2480
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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