product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Glutamate decarboxylase 2
catalog :
MBS963250
quantity :
0.05 mg (E-Coli)
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS963250
products type :
Recombinant Protein
products full name :
Recombinant Mouse Glutamate decarboxylase 2
products short name :
Glutamate decarboxylase 2
products name syn :
65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform
other names :
glutamate decarboxylase 2; Glutamate decarboxylase 2; glutamic acid decarboxylase 2; 65 kDa glutamic acid decarboxylase; GAD-65; Glutamate decarboxylase 65 kDa isoform
products gene name :
Gad2
other gene names :
Gad2; Gad2; GAD65; Gad-2; GAD(65); 6330404F12Rik; Gad65; GAD-65
uniprot entry name :
DCE2_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-585; Full length.
sequence length :
585
sequence :
MASPGSGFWSFGSEDGSADPENPGTARAWCQVAQKFTGG
IGNKLCALLYGDSGKPAEGGGSVTSRAATGKVACTCDQK
PCNCPKGDVNYAFLHATDLLPACDGERPTLAFLQDVMNI
LLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNL
EEILTHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADW
LTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGS
GDGIFSPGGAISNMYAMLIARYKMFPEVKEKGMAAVPRL
IAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIP
SDLERRILEVKQKGFVPFLVSATAGTTVYGAFDPLLAVA
DICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSV
TWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQ
DKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFE
AHIDKCLELAEYLYTIIKNREGYEMVFDGKPQHTNVCFW
FVPPSLRTLEDNEERMSRLSKVAPVIKARMMEYGTTMVS
YQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
Catalyzes the production of GABA.
products references :
Cloning and sequence analysis of a murine cDNA encoding glutamate decarboxylase (GAD65) .Lee D.S., Tian J., Phan T., Kaufman D.L.Biochim. Biophys. Acta 1216:157-160(1993) Mice lacking the 65 kDa isoform of glutamic acid decarboxylase (GAD65) maintain normal levels of GAD67 and GABA in their brains but are susceptible to seizures.Asada H., Kawamura Y., Maruyama K., Kume H., Ding R.G., Ji F.Y., Kanbara N., Kuzume H., Sanbo M., Yagi T., Obata K.Biochem. Biophys. Res. Commun. 229:891-895(1996) Localization and quantitation of expression of two glutamate decarboxylase genes in pancreatic beta-cells and other peripheral tissues of mouse and rat.Faulkner-Jones B.E., Cram D.S., Kun J., Harrison L.C.Endocrinology 133:2962-2972(1993)
ncbi gi num :
124517709
ncbi acc num :
NP_032104.2
ncbi gb acc num :
NM_008078.2
uniprot acc num :
P48320
ncbi mol weight :
69.3kD
ncbi pathways :
Alanine And Aspartate Metabolism Pathway (198303); Alanine, Aspartate And Glutamate Metabolism Pathway (101155); Alanine, Aspartate And Glutamate Metabolism Pathway (100063); Biogenic Amine Synthesis Pathway (198386); Butanoate Metabolism Pathway (83205); Butanoate Metabolism Pathway (391); GABA (gamma-Aminobutyrate) Shunt Pathway (421811); GABA (gamma-Aminobutyrate) Shunt Pathway (468220); GABA Synthesis Pathway (1323460); GABA Synthesis, Release, Reuptake And Degradation Pathway (1323459)
uniprot summary :
GAD2: Catalyzes the production of GABA. Homodimer. Belongs to the group II decarboxylase family. Protein type: Other Amino Acids Metabolism - beta-alanine; Amino Acid Metabolism - alanine, aspartate and glutamate; Carbohydrate Metabolism - butanoate; Lyase; Other Amino Acids Metabolism - taurine and hypotaurine; EC 4.1.1.15. Cellular Component: axon; cell junction; cytoplasm; cytoplasmic vesicle; cytosol; Golgi apparatus; membrane; perinuclear region of cytoplasm; plasma membrane; synapse; synaptic vesicle membrane. Molecular Function: carboxy-lyase activity; catalytic activity; glutamate binding; glutamate decarboxylase activity; lyase activity; protein heterodimerization activity; pyridoxal phosphate binding. Biological Process: carboxylic acid metabolic process; glutamate decarboxylation to succinate; neurotransmitter biosynthetic process
size1 :
0.05 mg (E-Coli)
price1 :
190 USD
size2 :
0.2 mg (E-Coli)
price2 :
460
size3 :
0.5 mg (E-Coli)
price3 :
750
size4 :
0.05 mg (Baculovirus)
price4 :
950
size5 :
0.05 mg (Mammalian-Cell)
price5 :
1170
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!