catalog number :
MBS963041
products type :
Recombinant Protein
products full name :
Recombinant Human Alpha-N-acetylglucosaminidase (NAGLU)
products short name :
Alpha-N-acetylglucosaminidase (NAGLU)
other names :
alpha-N-acetylglucosaminidase; Alpha-N-acetylglucosaminidase; alpha-N-acetylglucosaminidase; N-acetyl-alpha-glucosaminidase; N-acetylglucosaminidase, alpha; N-acetyl-alpha-glucosaminidase; NAG
products gene name :
NAGLU
other gene names :
NAGLU; NAGLU; NAG; MPS3B; UFHSD; MPS-IIIB; UFHSD1; NAG
uniprot entry name :
ANAG_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
24-743
sequence :
DEAREAA AVRALVARLL GPGPAADFSV SVERALAAKP GLDTYSLGGG GAARVRVRGS TGVAAAAGLH RYLRDFCGCH VAWSGSQLRL PRPLPAVPGE LTEATPNRYR YYQNVCTQSY SFVWWDWARW EREIDWMALN GINLALAWSG QEAIWQRVYL ALGLTQAEIN EFFTGPAFLA WGRMGNLHTW DGPLPPSWHI KQLYLQHRVL DQMRSFGMTP VLPAFAGHVP EAVTRVFPQV NVTKMGSWGH FNCSYSCSFL LAPEDPIFPI IGSLFLRELI KEFGTDHIYG ADTFNEMQPP SSEPSYLAAA TTAVYEAMTA VDTEAVWLLQ GWLFQHQPQF WGPAQIRAVL GAVPRGRLLV LDLFAESQPV YTRTASFQGQ PFIWCMLHNF GGNHGLFGAL EAVNGGPEAA RLFPNSTMVG TGMAPEGISQ NEVVYSLMAE LGWRKDPVPD LAAWVTSFAA RRYGVSHPDA GAAWRLLLRS VYNCSGEACR GHNRSPLVRR PSLQMNTSIW YNRSDVFEAW RLLLTSAPSL ATSPAFRYDL LDLTRQAVQE LVSLYYEEAR SAYLSKELAS LLRAGGVLAY ELLPALDEVL ASDSRFLLGS WLEQARAAAV SEAEADFYEQ NSRYQLTLWG PEGNILDYAN KQLAGLVANY YTPRWRLFLE ALVDSVAQGI PFQQHQFDKN VFQLEQAFVL SKQRYPSQPR GDTVDLAKKI FLKYYPRWVA GSW
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ncbi acc num :
NP_000254.2
ncbi gb acc num :
NM_000263.3
ncbi mol weight :
82,266 Da
ncbi pathways :
Disease Pathway 530764!!Glycosaminoglycan Degradation Pathway 82981!!Glycosaminoglycan Degradation Pathway 355!!Glycosaminoglycan Metabolism Pathway 645297!!HS-GAG Degradation Pathway 645307!!Heparan Sulfate Degradation Pathway 413377!!Heparan Sulfate Degradation Pathway 468270!!Heparan Sulfate/heparin (HS-GAG) Metabolism Pathway 645304!!Lysosome Pathway 99052!!Lysosome Pathway 96865
ncbi summary :
This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq, Jul 2008]
size :
1 mg (E Coli Derived)