Recombinant Human Actin, cytoplasmic 1 (ACTB) | MyBioSource MBS962728 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Actin, cytoplasmic 1 (ACTB)

catalog :

MBS962728

quantity :

0.5 mg (E-Coli)

price :

1145 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS962728

products type :

Recombinant Protein

products full name :

Recombinant Human Actin, cytoplasmic 1 (ACTB)

products short name :

Actin, cytoplasmic 1 (ACTB)

products name syn :

Actin, cytoplasmic 1; Beta-actinCleaved into the following chain:; 1. Actin, cytoplasmic 1, N-terminally processed

other names :

actin, cytoplasmic 1; Actin, cytoplasmic 1; actin, cytoplasmic 1; beta cytoskeletal actin; PS1TP5-binding protein 1; actin, beta; Beta-actinCleaved into the following chain:Actin, cytoplasmic 1, N-terminally processed

products gene name :

ACTB

other gene names :

ACTB; ACTB; BRWS1; PS1TP5BP1

uniprot entry name :

ACTB_HUMAN

host :

E Coli or Yeast or Baculovirus or Mammalian Cell

sequence positions :

1-375

sequence length :

375

sequence :

MDDDIAALVV DNGSGMCKAG FAGDDAPRAV FPSIVGRPRH QGVMVGMGQK DSYVGDEAQS KRGILTLKYP IEHGIVTNWD DMEKIWHHTF YNELRVAPEE HPVLLTEAPL NPKANREKMT QIMFETFNTP AMYVAIQAVL SLYASGRTTG IVMDSGDGVT HTVPIYEGYA LPHAILRLDL AGRDLTDYLM KILTERGYSF TTTAEREIVR DIKEKLCYVA LDFEQEMATA ASSSSLEKSY ELPDGQVITI GNERFRCPEA LFQPSFLGME SCGIHETTFN SIMKCDVDIR KDLYANTVLS GGTTMYPGIA DRMQKEITAL APSTMKIKII APPERKYSVW IGGSILASLS TFQQMWISKQ EYDESGPSIV HRKCF

purity :

>90%

form :

Liquid containing glycerol; lyophilization may be available upon request.

storage stability :

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

other info1 :

Species: Homo sapiens (Human)

products description :

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

ncbi gi num :

4501885

ncbi acc num :

NP_001092.1

ncbi gb acc num :

NM_001101.3

uniprot acc num :

P60709

ncbi mol weight :

41,737 Da

ncbi pathways :

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Arrhythmogenic Right Ventricular Cardiomyopathy Pathway (672454); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (117293); Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway (116129); Bacterial Invasion Of Epithelial Cells Pathway (149807); Bacterial Invasion Of Epithelial Cells Pathway (148661); Chaperonin-mediated Protein Folding Pathway (106242); Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway (106243); Dilated Cardiomyopathy Pathway (121494)

ncbi summary :

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008]

uniprot summary :

ACTB: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2. Interacts with GCET2. Belongs to the actin family. Protein type: Motility/polarity/chemotaxis; Cytoskeletal. Chromosomal Location of Human Ortholog: 7p22. Cellular Component: cortical cytoskeleton; extracellular space; NuA4 histone acetyltransferase complex; protein complex; focal adhesion; postsynaptic density; ribonucleoprotein complex; cytosol; nucleoplasm; cytoskeleton; membrane; axon; cytoplasm; nuclear chromatin; plasma membrane. Molecular Function: protein binding; nucleosomal DNA binding; structural constituent of cytoskeleton; kinesin binding; Tat protein binding; nitric-oxide synthase binding; protein kinase binding; ATP binding. Biological Process: intercellular junction assembly and maintenance; axon guidance; establishment and/or maintenance of chromatin architecture; protein folding; de novo posttranslational protein folding; retinal homeostasis; substantia nigra development; cellular protein metabolic process; ephrin receptor signaling pathway; ATP-dependent chromatin remodeling; innate immune response; blood coagulation; vascular endothelial growth factor receptor signaling pathway; cell motility. Disease: Dystonia, Juvenile-onset; Baraitser-winter Syndrome 1

size1 :

0.5 mg (E-Coli)

price1 :

1145 USD

size2 :

0.05 mg (Baculovirus)

price2 :

1145

size3 :

0.5 mg (Yeast)

price3 :

1375

size4 :

0.05 mg (Mammalian-Cell)

price4 :

1375

size5 :

1 mg (E-Coli)

price5 :

1825

more info or order :

MyBioSource product webpage