product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human N-myc proto-oncogene protein
catalog :
MBS962181
quantity :
0.05 mg (E-Coli)
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS962181
products type :
Recombinant Protein
products full name :
Recombinant Human N-myc proto-oncogene protein
products short name :
N-myc proto-oncogene
products name syn :
Class E basic helix-loop-helix protein 37; bHLHe37
other names :
N-myc proto-oncogene protein isoform 1; N-myc proto-oncogene protein; N-myc proto-oncogene protein; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; Class E basic helix-loop-helix protein 37; bHLHe37
products gene name :
MYCN
other gene names :
MYCN; MYCN; NMYC; ODED; MODED; N-myc; bHLHe37; BHLHE37; NMYC; bHLHe37
uniprot entry name :
MYCN_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-464
sequence length :
464
sequence :
MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGG
PDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPSWV
TEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMW
SGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAAS
PAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPF
PVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGV
APPRPGGRQTSGGDHKALSTS
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products categories :
Cancer
products description :
May function as a transcription factor.
products references :
Nucleotide sequence of the human N-myc gene.Stanton L.W., Schwab M., Bishop J.M.Proc. Natl. Acad. Sci. U.S.A. 83:1772-1776(1986)
ncbi gi num :
648216288
ncbi acc num :
NP_001280157.1
ncbi gb acc num :
NM_001293228.1
uniprot acc num :
P04198
ncbi mol weight :
51.56kD
ncbi pathways :
Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)
ncbi summary :
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
uniprot summary :
N-Myc: a proto-oncogenic transcription factor. Plays a role in cell proliferation, apoptosis and in the development of human tumors. Protein type: DNA-binding; Transcription factor; Oncoprotein. Chromosomal Location of Human Ortholog: 2p24.3. Cellular Component: chromatin; nucleus. Molecular Function: DNA binding; protein binding; protein dimerization activity; transcription factor activity. Biological Process: positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent. Disease: Feingold Syndrome 1; Tracheoesophageal Fistula With Or Without Esophageal Atresia
size1 :
0.05 mg (E-Coli)
price1 :
190 USD
size2 :
0.2 mg (E-Coli)
price2 :
460
size3 :
0.5 mg (E-Coli)
price3 :
750
size4 :
1 mg (E-Coli)
price4 :
1180
size5 :
0.05 mg (Baculovirus)
price5 :
1245
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!