catalog number :
MBS961856
products type :
Recombinant Protein
products full name :
Recombinant Macaca mulatta (Rhesus macaque) Synaptosomal-associated protein 25 (SNAP25)
products short name :
(Rhesus macaque) Synaptosomal-associated protein 25 (SNAP25)
products name syn :
Recombinant (Rhesus macaque) Synaptosomal-associated protein 25 (SNAP25); Synaptosomal-associated protein 25; SNAP-25; Synaptosomal-associated 25 kDa protein
other names :
synaptosomal-associated protein 25; Synaptosomal-associated protein 25; synaptosomal-associated protein 25; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein 25 isoform SNAP25B; Synaptosomal-associated 25 kDa protein
products gene name syn :
SNAP25
other gene names :
SNAP25; SNAP25; SNAP-25; SNAP-25
uniprot entry name :
SNP25_MACMU
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-206
sequence :
MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEES
KDAGIRTLVMLDEQGEQLERIEEGMDQINKDMKEAEKNL
TDLGKFCGLCVCPCNKLKSSDAYKKAWGNNQDGVVASQP
ARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGI
IGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEA
NQRATKMLGSG
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Macaca mulatta (Rhesus macaque)
ncbi acc num :
NP_001028036.1
ncbi gb acc num :
NM_001032864.1
ncbi mol weight :
23,315 Da
ncbi pathways :
SNARE Interactions In Vesicular Transport Pathway (86727); SNARE Interactions In Vesicular Transport Pathway (467)
uniprot summary :
Function: t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF . By similarity. Subunit structure: Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. This complex binds CPLX1. Interacts with CENPF, TRIM9, RIMS1, SNAPIN, OTOF and HGS. Binds STXBP6. Found in a ternary complex with STX1A and VAMP8. Found in a complex containing SYT1, SV2B and syntaxin-1. Associates with the BLOC-1 complex. Interacts with BLOC1S6 . By similarity. Interacts with EQTN . By similarity. Subcellular location: Cytoplasm perinuclear region . By similarity. Cell membrane; Lipid-anchor . By similarity. Cell junction synapse synaptosome . By similarity. Note: Membrane association requires palmitoylation. Expressed throughout cytoplasm, concentrating at the perinuclear region . By similarity. Post-translational modification: Palmitoylated. Cys-85 appears to be the main site, and palmitoylation is required for membrane association . By similarity. Sequence similarities: Belongs to the SNAP-25 family.Contains 2 t-SNARE coiled-coil homology domains.