product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Liver carboxylesterase 1 (CES1)
catalog :
MBS961237
quantity :
1 mg (E Coli Derived
price :
2230 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS961237
products type :
Recombinant Protein
products full name :
Recombinant Human Liver carboxylesterase 1 (CES1)
products short name :
Liver carboxylesterase 1 (CES1)
other names :
liver carboxylesterase 1 isoform b; Liver carboxylesterase 1; liver carboxylesterase 1; egasyn; serine esterase 1; retinyl ester hydrolase; cocaine carboxylesterase; triacylglycerol hydrolase; carboxylesterase 2 (liver); brain carboxylesterase hBr1; cholesteryl ester hydrolase; monocyte/macrophage serine esterase; methylumbelliferyl-acetate deacetylase 1; acyl coenzyme A:cholesterol acyltransferase; acyl-coenzyme A:cholesterol acyltransferase; human monocyte/macrophage serine esterase 1; carboxylesterase 1 (monocyte/macrophage serine esterase 1); carboxylesterase 1; Acyl-coenzyme A:cholesterol acyltransferase; ACAT; Brain carboxylesterase hBr1; Carboxylesterase 1 (EC:3.1.1.1); CE-1; hCE-1; Cocaine carboxylesterase; Egasyn; HMSE; Methylumbelliferyl-acetate deacetylase 1 (EC:3.1.1.56); Monocyte/macrophage serine esterase; Retinyl ester hydrolase; REH; Serine esterase 1; Triacylglycerol hydrolase; TGH
products gene name :
CES1
other gene names :
CES1; CES1; CEH; REH; TGH; ACAT; CE-1; CES2; HMSE; SES1; HMSE1; PCE-1; hCE-1; CES2; SES1; ACAT; CE-1; hCE-1; REH; TGH
uniprot entry name :
EST1_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
18-567
sequence length :
567
sequence :
GHP SSPPVVDTVH GKVLGKFVSL EGFAQPVAIF LGIPFAKPPL GPLRFTPPQP AEPWSFVKNA TSYPPMCTQD PKAGQLLSEL FTNRKENIPL KLSEDCLYLN IYTPADLTKK NRLPVMVWIH GGGLMVGAAS TYDGLALAAH ENVVVVTIQY RLGIWGFFST GDEHSRGNWG HLDQVAALRW VQDNIASFGG NPGSVTIFGE SAGGESVSVL VLSPLAKNLF HRAISESGVA LTSVLVKKGD VKPLAEQIAI TAGCKTTTSA VMVHCLRQKT EEELLETTLK MKFLSLDLQG DPRESQPLLG TVIDGMLLLK TPEELQAERN FHTVPYMVGI NKQEFGWLIP MQLMSYPLSE GQLDQKTAMS LLWKSYPLVC IAKELIPEAT EKYLGGTDDT VKKKDLFLDL IADVMFGVPS VIVARNHRDA GAPTYMYEFQ YRPSFSSDMK PKTVIGDHGD ELFSVFGAPF LKEGASEEEI RLSKMVMKFW ANFARNGNPN GEGLPHWPEY NQKEGYLQIG ANTQAAQKLK DKEVAFWTNL FAKKAVEKPP QTEHIEL
purity :
>90%
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
other info1 :
Tag Information: His tagged (Host tag may vary. Please inquire for specific tag information). Species: Homo sapiens (Human)
other info2 :
Storage Buffer: Tris-based buffer,50% glycerol. Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
products description :
CES1; CES2, SES1
ncbi gi num :
68508965
ncbi acc num :
NP_001020365.1
ncbi gb acc num :
NM_001025194.1
uniprot acc num :
P23141
ncbi mol weight :
62,393 Da
ncbi pathways :
Drug Metabolism - Other Enzymes Pathway 83033!!Drug Metabolism - Other Enzymes Pathway 428!!E2F Transcription Factor Network Pathway 137934!!Fluoropyrimidine Activity Pathway 198778!!Irinotecan Pathway 198905!!Metabolic Pathways 132956!!Retinol Biosynthesis Pathway 545450!!Retinol Biosynthesis Pathway 545293
ncbi summary :
This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
size :
1 mg (E Coli Derived)
price :
2230 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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