catalog number :
MBS961165
products type :
Recombinant Protein
products full name :
Recombinant Macaca mulatta (Rhesus macaque) Beta-1 adrenergic receptor (ADRB1)
products short name :
(Rhesus macaque) Beta-1 adrenergic receptor (ADRB1)
products name syn :
Recombinant (Rhesus macaque) Beta-1 adrenergic receptor (ADRB1); Beta-1 adrenergic receptor; Beta-1 adrenoreceptor; Beta-1 adrenoceptor
other names :
Beta-1 adrenergic receptor; Beta-1 adrenergic receptor; Beta-1 adrenoreceptor
products gene name syn :
ADRB1
other gene names :
ADRB1; Beta-1 adrenoceptor
uniprot entry name :
ADRB1_MACMU
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-480
sequence :
MGAGALVLGASEPGNLSSAAPLPDGVATAARLLVPASPP
ASLLPPASEGPEPLSQQWTAGMGLLMALIVLLIVAGNVL
VIVAIAKTPRLQTLTNLFIMSLASADLVMGLLVVPFGAT
IVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDR
YLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPIL
MHWWRAESDEARRCYNDPKCCDFVTNRAYAIASSVVSFY
VPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGGPARPP
SPSPSPSPSPVPAPPPGPPRPAAAAATTAPLVNGRAGKR
RPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANVVKA
FHRELVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRNAF
QRLLCCARRAARRRHAAHGDRPRASGCLARPGPPPSPGA
ASDDDDDDVVGATQPARLLEPWAGCNGGAAADSDSSLDE
PCRPGFASESKV
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
other info1 :
Species: Macaca mulatta (Rhesus macaque)
ncbi mol weight :
51,609 Da
ncbi pathways :
Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); MAPK Signaling Pathway (83048); MAPK Signaling Pathway (456); Salmonella Infection Pathway (375172); Salmonella Infection Pathway (375149)
uniprot summary :
Function: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. Subunit structure: Interacts with GOPC, MAGI3 and DLG4 . By similarity. Subcellular location: Cell membrane; Multi-pass membrane protein . By similarity. Note: Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression . By similarity. Domain: The PDZ domain-binding motif mediates competitive interactions with GOPC, MAGI3 and DLG4 and plays a role in subcellular location of the receptor . By similarity. Post-translational modification: Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase. Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.